Summary
The assignment of the human prealbumin (PALB) gene to chromosome region 18q11–q12.1 has been achieved using a human genomic probe in the study of human-mouse somatic cell hybrids and by in situ hybridization. Because familial amyloidotic polyneuropathy was reported previously to be due to a mutation in prealbumin, it can be inferred that the gene for this disorder also maps to 18q11.2–q12.1.
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Sparkes, R.S., Sasaki, H., Mohandas, T. et al. Assignment of the prealbumin (PALB) gene (familial amyloidotic polyneuropathy) to human chromosome region 18q11.2–q12.1. Hum Genet 75, 151–154 (1987). https://doi.org/10.1007/BF00591077
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DOI: https://doi.org/10.1007/BF00591077