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Effects on rats of CSF from sleep-deprived rabbits

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Summary

Rabbits were sleep-deprived for 72 hours in revolving drum sleep deprivation cages. Cerebrospinal fluid samples obtained from these sleep-deprived and from control rabbits were infused intraventricularly into rats to assay for the presence of a sleep-promoting material in the sleep-deprived rabbit CSF. Effects on ECoG patterns, ambulatory activity and behavior of the assay rats failed to show sleep-promoting properties for the CSF from sleep-deprived rabbits.

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Authors and Affiliations

  1. Life Sciences Division, Midwest Research Institute, 425 Volker Boulevard, 64110, Kansas City, Missouri, USA

    David A. Ringle & Betty L. Herndon

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  1. David A. Ringle
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  2. Betty L. Herndon
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Ringle, D.A., Herndon, B.L. Effects on rats of CSF from sleep-deprived rabbits. Pflugers Arch. 306, 320–328 (1969). https://doi.org/10.1007/BF00589157

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  • DOI: https://doi.org/10.1007/BF00589157

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