Abstract
A 28-year-old female farmer, without vascular risk factors, developed a limited infarct of the pons, associated with a lymphocytic cerebrospial fluid (CSF) pleocytosis. Titres of specific antibodies againstBorrelia burgdorferi were high in serum and CSF. MRI confirmed an infarct in the territory of the medial pontine arteries, but angiography showed no, evidence of cerebral angiopathy. Antibiotic therapy rapidly led to a return to normal of CSF cytology and serology. We suggest that Lyme disease is a possible cause of cerebral ischaemia.
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Uldry PA, Bogousslavsky J, Regli F, Kuntzer T (1991) Neuroborréliose et maladie de Lyme. In: Encycl Méd Chir 17051. Neurologie, Editions Techniques, Paris, p 6
Rafto SE, Milton WJ, Galetta SL, Grossman RI (1990) Biopsyconfirmed CNS Lyme disease: MR appearance at 1.5 T. AJNR 11:482–484
Fernández RE, Rothberg M, Ferencz G, Wujack D (1990) Lyme disease of the CNS: MR imaging findings in 14 cases. AJNR 11: 479–481
Anderson JF, Doby JM, Couatarmanac'h A, Hyde FW, Johnson RC (1986) Différence antigéniques entre des souches deBorrelia burgdorferi isolées deIxodes ricinus en Bretagne. Méd Mal Infect 16:171–175
Wilske B, Schierz G, Preac-Mursic V, Von Busch R, Kuhbeck R, Pfister HW, Einhpaul K (1986) Intrathecal production of specific antibodies againstBorrelia burgdorferi in patients with lymphocytic meningoradiculitis (Bannworth's syndrome). J Infect Dis 153:304–314
Stiernstedt GT, Granstrom M, Hederstedt B, Skoldenberg B (1985) Diagnosis of spirochetal meningitis by enzyme-linked immunosorbent assay and indirect immunofluorescence assay in serum and cerebrospinal fluid. J Clin Microbiol 21:819–825
Pfister HW, Preac-Mursic V, Wilske B, Einhaupl KM (1989) Cefotaxime vs penicillin G for acute neurologic manifestations in Lyme borreliosis. Arch Neurol 46:1190–1194
Veenendal-Hilbers, Perquin WVM, Hoogland PH, Doornbos L (1988) Basal meningo-vasculitis and occlusion of the basilar artery in two cases ofBorrelia burgdorferi infection. Neurology 38: 1317–1319
Kohler J, Kern U, Kasper J, Rheese-Kupper B, Thoten U (1988) Chronic central nervous system involvement in Lyme borreliosis. Neurology 38:863–867
Uldry PA, Regli F, Bogousslavsky J (1987) Cerebral angiopathy and recurrent strokes followingBorrelia burgdorferi infection. J Neurol Neurosurg Psychiatry 50:1703–1704
Wokke JHJ, Van Gijn J, Elderson A, Stanek G (1987) Chronic forms ofBorrelia burgdorferi infection of the nervous system. Neurology 37:1031–1034
Midgard R, Hofstad H (1987) Unusual manifestations of nervous systemBorrelia burgdorferi infection. Arch Neurol 4: 781–783
Kuntzer T, Bogousslavsky J, Miklossy J, Steck AJ, Janzer R, Regli F (1991) Borrelia rhombencephalomyelopathy. Arch Neurol 48:832–836
May EF, Jabbari B (1990) Stroke in neuroborreliosis. Stroke 21: 1232–1235
Finkel MF (1988) Lyme disease and its neurologic complications. Arch Neurol 45:99–104
Logigian EL, Kaplan RF, Steere AC (1990) Chronic neurologic manifestations of Lyme disease. N Engl J Med 323:1438–1444
Halperin JJ, Luft BJ, Anand AK, Roque CT, Alvarez O, Volkman DJ, Dattwyler RJ (1989) Lyme neuroborreliosis: central nervous system manifestations. Neurology 39:753–759
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Defer, G., Levy, R., Brugiéres, P. et al. Lyme disease presenting as a stroke in the vertebrobasilar territory: MRI. Neuroradiology 35, 529–531 (1993). https://doi.org/10.1007/BF00588714
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DOI: https://doi.org/10.1007/BF00588714