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Cerebrospinal fluid flow

II. Physiology of respiration-related pulsations

  • Diagnostic Neuroradiology
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Summary

Cerebrospinal fluid (CSF) flow in the cerebral aqueduct and spinal canal was analysed using real-time magnetic resonance imaging measurement techniques. Respiration-induced rhythmic modulation of the cardiacrelated oscillating CSF pulsation in the cerebral aqueduct and spinal canal was found. Deep inspiration was immediately followed by a marked increase in downward CSF flow in the cervical spinal canal, whereas a delay of about two heart beats was seen before downward flow from the third to the fourth ventricle increased. This pattern was also detected during yawning and was followed by a marked increase of blood flow in the internal jugular vein.

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References

  1. Bergstrand G, Bergstroem M, Nordell B, et al (1985) Cardiac gated MR imaging of cerebrospinal fluid flow. J Comput Assist Tomogr 9: 1003–1006

    Google Scholar 

  2. Feinberg DA, Marks AS (1987) Human brain motion and cerebrospinal fluid circulation demonstrated with MR velocity imaging. Radiology 163:793–799

    Google Scholar 

  3. Quencer RM, Post MD, Hinks RS (1990) Cine MR in the evaluation of normal and abnormal CSF flow: intracranial and intraspinal studies. Neuroradiology 32: 371–391

    Google Scholar 

  4. Schroth G, Klose U, Gawehn J, Petersen D, Varallay G (1987) ECG-related pulsations of the CSF. Society of Magnetic Resonance in Medicine, 6th Annual Meeting, New York, Book of Abstracts, p 119

  5. Schroth G, Klose U, Grodd W (1989) Spinal CSF pulsations. In: Nadjimi M (ed) Imaging of brain metabolism, spine and cord, Springer, Berlin Heidelberg New York, pp 53–58

    Google Scholar 

  6. Schroth G, Klose U (1992) Cerebrospinal flow. I. Physiology of cardiac-related pulsations. Neuroradiology 35: 1–9

    Google Scholar 

  7. Knoll P (1886) Ueber die Druckschwankungen in der Cerebrospinalfluessigkeit und den Wechsel in der Blutfuelle des centralen Nervensystems. Sitzungsber Kaiserl Akad Wiss Wien Math-Naturwiss Classe 1886: 217–248

    Google Scholar 

  8. Becher E (1919) Beobachtungen ueber die Abhaengigkeit des Lumbaldruckes von der Kopfhaltung. Dtsch Z Nervenheilkd 63: 89–96

    Google Scholar 

  9. Becher E (1924) Ueber Druckverhaeltnisse im Liqour cerebrospinalis. Grenzgeb Med Chir 35: 324–332

    Google Scholar 

  10. Di Chiro G (1964) Movement of the cerebrospinal fluid in human beings. Nature 204: 290–291

    Google Scholar 

  11. Di Chiro G (1966) Observations on the circulation of the cerebrospinal fluid. Acta Radiol 5: 988–1002

    Google Scholar 

  12. Di Chiro G, Hammock MK, Bleyer WA (1976) Spinal descent of cerebrospinal fluid in man. Neurology 26: 1–8

    Google Scholar 

  13. Du Boulay GH (1966) Pulsatile movements in the CSF pathways. Br J Radiol 39: 255–262

    Google Scholar 

  14. Du Boulay GH, O'Connell J, Currie J, Bostick T, Verity P (1972) Further investigations on pulsatile movements in the cerebrospinal fluid pathways. Acta Radiol 13: 496–523

    Google Scholar 

  15. Klose U, Schroth G, Mueller E, Grodd W (1988) Echtzeit-Darstellungsmoeglichkeiten von Liquorbewegungen in der Kernspintomographie. In: Nüsslin F (ed) Medizinische Physik. Deutsche Gesellschaft fuer Med. Physik, Tübingen, pp 562–567

  16. Mueller E, Laub G, Graumann R, Loeffler W (1988) RACE-real time acquisition and evaluation of pulsatile blood flow on a whole body MRI unit. Society of Magnetic Resonance in Medicine, 7th Annual Meeting, San Francisco, Book of Abstracts, p 729

  17. Quinke H (1877) Ueber den Druck in Transsudaten. Arch Klin Med 21: 453–468

    Google Scholar 

  18. Ewig W, Lullies H (1924) Der Einfluss der Atmung auf die Druckschwankungen im Cerebrospinalkanal. Z Exp Med 43: 764–781

    Google Scholar 

  19. Fleck U (1932) Zur Bewertung des Liquordrucks. Dtsch Med Wochenschr 1: 737–740

    Google Scholar 

  20. Ewig W, Lullies H (1924) Ueber die pulsatorischen Druckschwankungen im Lumbalkanal. Z Exp Med 43: 782–790

    Google Scholar 

  21. Sharpey-Schafer EP (1965) Effect of respiratory acts on the circulation. In: Hamilton WF, Dow P (eds) Physiology, section 2, vol 3. Circulation. Waverly Press, Baltimore, pp 1875–1886

    Google Scholar 

  22. Milhorat TH (1975) The third circulation revisited. J Neurosurg 42: 628–645

    Google Scholar 

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Authors and Affiliations

  1. Department of Neuroradiology, University of Tübingen, Federal Republic of Germany

    G. Schroth & U. Klose

  2. Department of Neuroradiology, Eberhard-Karls-Universität, Hoppe-Seyler-Strasse 3, W-7400, Tübingen, Federal Republic of Germany

    G. Schroth

Authors
  1. G. Schroth
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  2. U. Klose
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Schroth, G., Klose, U. Cerebrospinal fluid flow. Neuroradiology 35, 10–15 (1992). https://doi.org/10.1007/BF00588271

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  • DOI: https://doi.org/10.1007/BF00588271

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