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A chemical investigation ofAchillea nobilis

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Abstract

From the flower heads and leaves ofAchillea nobilis collected in the flowering phase close to Balytkykol, Egindybulak region, Karaganda Province, Kazakh SSR, by extraction with chloroform and chromatography of the combined substances on a column of silica gel we have isolated a new sesquiterpene lactone anobin C15H20O5, mp 175.5–177.5°C and have identified for the first time estafiatin, C15H18O3, mp 102–104°C [α]20 −10.3° (chloroform); hanphyllin, C15H20O3, mp 189°C (decomp), [α] 20D + 58.6° (c 0.39; chloroform), and 3,5-dihydroxy-6,7,8-trimethoxyflavone, C18H16O7, mp 148–150°C. On the basis of chemical and spectral characteristics it has been established that anobin has the structure of 4α,10α-dihydroxy-2α,3α-epoxy-5,7α(H),6β(H)-guai-11(13)-en-6,12-olide. It has been established that estafiatin possesses a pronounced growth regulating activity.

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Literature cited

  1. S. M. Adekenov, A. N. Kupriyanov, M. N. Mukhametzhanov, and K. A. Aituganov, "The growth-regulating activity of the extractive substances of some plants of the familyCompositae," paper deposited at VINITI, No. 358–80 Dep. (1980).

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Authors
  1. S. M. Adekenov
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  2. M. N. Mukhametzhanov
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  3. A. D. Kagarlitskii
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  4. A. Zh. Turmukhambetov
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Additional information

Deceased.

Chemical and Metallurgical Institute, Academy of Sciences of the Kazakh SSR, Karaganda. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 603–607, September–October, 1984.

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Adekenov, S.M., Mukhametzhanov, M.N., Kagarlitskii, A.D. et al. A chemical investigation ofAchillea nobilis . Chem Nat Compd 20, 568–571 (1984). https://doi.org/10.1007/BF00580067

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  • DOI: https://doi.org/10.1007/BF00580067

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