Abstract
A genetic polymorphism of sorbitol dehydrogenase (SDH; EC 1.1.1.14) for two allozymes is demonstrated in the brown hare (Lepus europaeus) by means of horizontal starch gel electrophoresis. Segregation analysis was performed in a sample of four matings with 12 offspring and confirmed the genetic hypothesis: two alleles at an autosomal locus. The calculated gene frequencies in the brown hare breed studied areSdh a=0.712 andSdh b=0.288. The distribution of the polymorphism in free-ranging brown hare populations from Austria, Czechoslovakia, Hungary, and Poland is described.
Similar content being viewed by others
References
Andrews, S. J., and Peters, J. (1983). Linkage analyses and biochemical genetics of sorbitol dehydrogenase-1 (Sdh-1) in the mouse.Biochem. Genet. 21809.
Baccus, R., and Wolff, J. O. (1989). Genetic composition of fluctuating populations ofPeromyscus leucopus andPeromyscus maniculatus.J. Mamm. 70592.
Baccus, R., Hillestad, H. O., Johns, P. E., Manlove, M. N., Marchinton, R. L., and Smith, M. H. (1977). Prenatal selection in white-tailed deer.Proc. Annu. Conf. S.E. Assoc. Fish Wildl. Agencies 31173.
Benmehdi, F., Britton-Davidian, J., and Thaler, L. (1980). Premier apport de la génétique biochimique des populations à la systématique des mulots de France Continentale et de Corse.Biochem. Syst. Ecol. 8309.
Bonhomme, F., Catalan, J., Britton-Davidian, J., Chapman, V., Moriwaki, K., Nevo, E., and Thaler, L. (1984). Biochemical diversity and evolution in the genusMus.Biochem. Genet. 22275.
Bonhomme, F., Fernandez, J., Palacios, F., Catalan, J., and Machordon, A. (1986). Caractérisation biochimique du complexe d'espèces du genreLepus en Espagne.Mammalia 50495.
Breshears, D. D., Smith, M. H., Cothran, E. G., and Johns, P. E. (1988). Genetic variability in white-tailed deer.Heredity 60139.
Csaikl, F., Engel, W., and Schmidtke, J. (1980). On the biochemical systematics of threeApodemus species.Comp. Biochem. Physiol. 65B411.
Daly, J. C. (1981). Effects of social organization and environmental diversity on determining the genetic structure of a population of the wild rabbit,Oryctolagus cuniculus.Evolution 35689.
Glover, D. G., Smith, M. H., Ames, L., Joule, J., and Dubach, J. M. (1977). Genetic variation in pika populations.Can J. Zool. 551841.
Grillitsch, M. (1990).Biochemisch-systematische Untersuchungen an ausgewählten Vertretern der Lagomorphen und dreier weiterer Plazentalia-Ordnungen Unpublished Ph.D. thesis, University of Vienna, Vienna.
Harris, H. (1980).The Principles of Human Biochemical Genetics North-Holland, Amsterdam.
Harris, H., and Hopkinson, D. A. (1976).Handbook of Enzyme Electrophoresis in Human Genetics North-Holland, Amsterdam.
Hartl, G. B. (1987). Biochemical differentiation between the Wild rabbit (Oryctolagus cuniculus L.), the Domestic rabbit and the Brown hare (Lepus europaeus Pallas).Z. Zool. Syst. Evolut.-forsch. 25309.
Hartl, G. B., and Höger, H. (1986). Biochemical variation in purebred and crossbred strains of domestic rabbits (Oryctolagus cuniculus L.).Genet. Res. Cambr. 4827.
Hartl, G. B., Willing, R., Grillitsch, M., and Klansek, E. (1988). Biochemical variation in Mustelidae: Are carnivores genetically less variable than other mammals.Zool. Anz. 22181.
Hartl, G. B., Suchentrunk, F., Willing, R., and Grillitsch, M. (1989). Biochemisch-genetische Variabilität und Differenzierung beim Feldhasen (Lepus europaeus) in Niederösterreich.Wien. Tierärztl. Mschr. 76279.
Hartl, G. B., Markowski, J., Kovacs, G., Grillitsch, M., and Willing, R. (1990a). Biochemical variation and differentiation in the Brown hare (Lepus europaeus) of Central Europe.Z. Säugetierkunde 55186.
Hartl, G. B., Willing, R., and Suchentrunk, F. (1990b). On the biochemical systematics of selected mammalian taxa: Empirical comparison of qualitative and quantitative approaches in the evaluation of protein electrophoretic data.Z. zool. Syst. Evolut.-forsch 28191.
Johnson, G. B. (1974). Enzyme polymorphism and metabolism.Science 18428.
Kaneko, J. J. (ed.) (1980).Clinical Biochemistry of Domestic Animals Academic Press, New York.
Manlove, M. N., Avise, J. C., Hillestad, H. O., Ramsey, P. R., Smith, M. H., and Straney, D. O. (1975). Starch gel electrophoresis for the study of population genetics in white-tailed deer.Proc. Ann. Conf. S.E. Game Fish Comm. 29392.
Nevo, E., Kim, Y. J., Shaw, C. R., and Thaeler, C. S. Jr. (1974). Genetic variation, selection and speciation inThomomys talpoides pocket gophers.Evolution 281.
Op't Hof, J. (1969). Isoenzymes and population genetics of sorbit dehydrogenase (EC: 1.1.1.14) in swine (Sus scrofa).Humangenetik 7258.
Op't Hof, J., Wolf, U., and Krone, W. (1969). Studies on isozymes of sorbitol dehydrogenase in some vertebrate species.Humangenetik 8178.
Op't Hof, J., Osterhoff, D. R., and de Beer, G. (1972). Polymorphism of sorbitol dehydrogenase and 6-phosphogluconate dehydrogenase in swine (Sus scrofa).Anim. Blood Grps. Biochem. Genet. 3237.
Richardson, B. J. (1980). Ecological genetics of the wild rabbit in Australia. III. Comparison of the microgeographical distribution of alleles in two different environments.Aust. J. Biol. Sci. 33385.
Richardson, B. J. (1981). The genetic structure of rabbit populations. In Myers, K., and MacInnes, C. D. (eds.),Proceedings of the World Lagomorph Conference Held in Guelph, Ontario, August 1979 University of Guelph, Guelph, pp. 37–52.
Richardson, B. J., Rogers, P. M., and Hewitt, G. M. (1980). Ecological genetics of the wild rabbit in Australia. II. Protein variation in British, French and Australian rabbits and the geographical distribution of the variation in Australia.Aust. J. Biol. Sci. 33371.
Schröder, J., Soveri, T., Suomalainen, H. A., Lindberg, L.-A., and Van der Loo, W. (1987). Hybrids betweenLepus timidus andLepus europaeus are rare although fertile.Hereditas 107185.
Shaw, C. R., and Prasad, R. (1970). Starch gel electrophoresis of enzymes—a compilation of recipes.Biochem. Genet. 4297.
Sheffield, S. R., Morgan, R. P., II, Feldhamer, G., and Harman, D. M. (1985). Genetic variation in white-tailed deer (Odocoileus virginianus) populations in western Maryland.J. Mamm. 66243.
Shows, T. B., and McAlpine, P. J. (1982). The 1981 catalogue of assigned human genetic markers and report of the nomenclature committee.Cytogenet. Cell. Genet. 32221.
Tolliver, D. K., Smith, M. H., Johns, P. E., and Smith, M. W. (1985). Low levels of genetic variability in pikas from Colorado.Can. J. Zool. 631735.
Ward, R. D. (1977). Relationship between enzyme heterozygosity and quaternary structure.Biochem. Genet. 15123.
Ward, R. D. (1978). Subunit size of enzymes and genetic heterozygosity in vertebrates.Biochem. Genet. 16799.
Author information
Authors and Affiliations
Additional information
This research was supported by a grant from the Fonds zur Förderung der Wissenschaftlichen Forschung, Austria (project P6767B).
Rights and permissions
About this article
Cite this article
Hartl, G.B. Genetic polymorphism of sorbitol dehydrogenase in the brown hare and the distribution of the variation in Central Europe. Biochem Genet 29, 49–54 (1991). https://doi.org/10.1007/BF00578239
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00578239