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Increased bioavailability of cimetidine with age?

Letter to the editor concerning the article “blood level of cimetidine in relation to age” by A. Redolfi, E. Borgogelli, and E. Lodola Eur. J. Clin. Pharmacol. 15, 257–261 (1979)

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References

  1. Gibaldi, M., Perrier, D.: Pharmacokinetics, pp 129–174. New York: Marcel Dekker 1975

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  2. Redolfi, A., Borgogelli, E., Lodola, E.: Blood level of cimetidine in relation to age. Eur. J. Clin. Pharmacol.15, 257–261 (1979)

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  3. Somogyi, A., Rohner, H., Gugler, R.: Pharmacokinetics and bioavailability of cimetidine in gastric and duodenal ulcer patients. Clin. Pharmacokinet. (in press, 1979)

  4. Walkenstein, S.S., Dubb, J.W., Randolph, W.C., Westlake, W.J., Stote, R.M., Intoccia, A.P.: Bioavailability of cimetidine in man. Gastroenterology74, 360–365 (1978)

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References

  1. Redolfi, A., Borgogelli, E., Lodola, E.: Blood level of cimetidine in relation to age. Eur. J. Clin. Pharmacol.15, 257–261 (1979)

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  2. U. S. Food and Drug Administration. Procedures for determining the bioavailability of drug products. Federal Register, January 7, 1977, Part III, pp. 1648–1653

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Somogyi, A., Gugler, R., Redolfi, A. et al. Increased bioavailability of cimetidine with age?. Eur J Clin Pharmacol 16, 431–433 (1979). https://doi.org/10.1007/BF00568207

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