Abstract
The present study provides an objective assessment of the increased talkativeness associated with acute opiate drug administration. Speech of five methadone-maintenance subjects was recorded continuously for 1 h following the injection of 0, 10, 14, or 18 mg hydromorphone. Dose-related increases in subjects' speech were observed, while no systematic changes were seen in speech of an undrugged partner. Dose-related increases were also obtained on an adjective checklist measuring characteristic opiate signs and symptoms. The relationship between behavioral, subjective, and reinforcing drug effects is discussed.
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Stitzer, M.L., McCaul, M.E., Bigleow, G.E. et al. Hydromorphone effects on human conversational speech. Psychopharmacology 84, 402–404 (1984). https://doi.org/10.1007/BF00555221
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DOI: https://doi.org/10.1007/BF00555221