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Ultrastructural studies of the effects of amprolium and dinitolmide on Eimeria acervulina macrogametes

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Abstract

Medication of chicks with 125 ppm amprolium or dinitolmide adversely affected oocyst sporulation of Eimeria acervulina (Weybridge strain). Dinitolmide delayed oocyst production and no oocyst wall formation was seen up to 168 h post infection. Both drugs caused large numbers of abnormally small wall-forming bodies to be produced in the macrogametes. In amprolium-fed chicks, abnormal oocyst wall formation was seen. It was concluded that the main drug action was against wall forming bodies of type 2.

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Abbreviations

C :

canaliculi

CL :

cytoplasmic limiting membrane

L :

lipid

M1, M2, M3 :

membranes

N :

nucleus

NU :

nucleolus

OW :

outer oocyst wall

PG :

polysaccharide granule

PV :

parasitophorous vacuole

WFB1 :

wall forming bodies of type 1

WFB2 :

wall forming bodies of type 2

References

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Authors and Affiliations

  1. Department of Biology and Biochemistry, North East London Polytechnic, Romford Road, E15 4LZ, London, UK

    S. J. Ball

  2. Department of Analytical and Biological Chemistry, Kingston Polytechnic, Penrhyn Road, KT1 2EE, Kingston upon Thames, UK

    R. M. Pittilo

  3. Central Veterinary Laboratory, MAFF, KT15 3NB, New Haw, Weybridge, Surrey, UK

    C. C. Norton & L. P. Joyner

Authors
  1. S. J. Ball
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  2. R. M. Pittilo
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  3. C. C. Norton
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  4. L. P. Joyner
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Ball, S.J., Pittilo, R.M., Norton, C.C. et al. Ultrastructural studies of the effects of amprolium and dinitolmide on Eimeria acervulina macrogametes. Parasitol Res 73, 293–297 (1987). https://doi.org/10.1007/BF00531080

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  • DOI: https://doi.org/10.1007/BF00531080

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