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The timing and sequence of events in the development of the human urinary system during the embryonic period proper

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Summary

A documented scheme of the early development of the human urinary system is presented. It is based on (1) reports of workers who personally studied staged embryos, and (2) personal observations and confirmations. The necessity of studying staged embryos in order to determine the precise sequence of developmental events is stressed.

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References

  • Chwalla, R.: Über die Entwicklung der Harnblase und der primären Harnröhre des Menschen mit besonderer Berücksichtigung der Art und Weise, in der sich die Ureteren von den Urnierengängen trennen, nebst Bemerkungen über die Entwicklung der Müllerschen Gänge und des Mastdarms. Z. Anat. Entwickl.-Gesch. 83, 615–733 (1927).

    Google Scholar 

  • Cooper, M. H., O'Rahilly, R.: The human heart at seven postovulatory weeks. Acta anat. (Basel) 79, 280–299 (1971).

    Google Scholar 

  • Davis, C. L.: Description of a human embryo having twenty paired somites. Contr. Embryol. Carneg. Instn 15, 1–51 (1923).

    Google Scholar 

  • Duhamel, B.: Morphogenèse pathologique. Paris: Masson 1966.

    Google Scholar 

  • Felix, W.: The development of the urinogenital organs. In: F. Keibel and F. P. Mall, Manual of human embryology, vol. 2, p. 752–979. Philadelphia: Lippincott 1912.

    Google Scholar 

  • Florian, J.: The formation of the connecting stalk and the extension of the amniotic cavity towards the tissue of the connecting stalk in young human embryos. J. Anat. (Lond.) 64, 454–476 (1930).

    Google Scholar 

  • Florian, J.: The early development of man, with special reference to the development of the mesoderm and cloacal membrane. J. Anat. (Lond.) 67, 263–276 (1933).

    Google Scholar 

  • Gage, S. P.: A three week's human embryo, with especial reference to the brain and the nephric system. Amer. J. Anat. 4, 409–443 (1905).

    Google Scholar 

  • Glenister, T. W.: The origin and fate of the urethral plate in man. J. Anat. (Lond.) 88, 413–425 (1954).

    Google Scholar 

  • Glenister, T. W.: The development of the utricle and of the so-called “middle” or “median” lobe of the human prostate. J. Anat. (Lond.) 96, 443–455 (1962).

    Google Scholar 

  • Gruenwald, P.: Primary asymmetry of the growing müllerian ducts in the chick embryo. J. Morph. 71, 299–305 (1942).

    Google Scholar 

  • Gruenwald, P.: The normal changes in the position of the embryonic kidney. Anat. Rec. 85, 163–176 (1943).

    Google Scholar 

  • Gyllensten, L.: Contributions to the embryology of the urinary bladder. Part 1. The development of the definitive relations between the openings of the Wolffian ducts and the ureters. Acta anat. (Basel) 7, 305–344 (1949).

    Google Scholar 

  • Hertig, A. T.: Human trophoblast. Springfield, Illinois: Thomas 1968.

    Google Scholar 

  • Hertig, A. T., Rock, J.: Two human ova of the pre-villous stage, having a developmental age of about eight and nine days respectively. Contr. Embryol. Carneg. Instn 33, 169–186 (1949).

    Google Scholar 

  • Heuser, C. H.: A presomite human embryo with a definite chorda canal. Contr. Embryol. Carneg. Instn 23, 251–267 (1932).

    Google Scholar 

  • Heuser, C. H., Corner G. W.: Developmental horizons in human embryos. Description of age group X, 4 to 12 somites. Contr. Embryol. Carneg. Instn 36, 29–39 (1957).

    Google Scholar 

  • Heuser, C. H., Rock, J., Hertig, A. T.: Two human embryos showing early stages of the definitive yolk sac. Contr. Embryol. Carneg. Instn 31, 85–99 (1945).

    Google Scholar 

  • Hilson, D.: Malformations of ears as sign of malformation of genito-urinary tract. Brit. med. J. 1957 II, 785–789.

    Google Scholar 

  • Hunter, R. H.: Observations on the development of the human female genital tract. Contr. Embryol. Carneg. Instn 22, 91–107 (1930).

    Google Scholar 

  • Ingalls, N. W.: A human embryo at the beginning of segmentation, with special reference to the vascular system. Contr. Embryol. Carneg. Instn 11, 61–90 (1920).

    Google Scholar 

  • Jirásek, J. E.: Development of the genital system and male pseudohermaphroditism. Baltimore: Johns Hopkins Press 1971.

    Google Scholar 

  • Koff, A. K.: Development of the vagina in the human fetus. Contr. Embryol. Carneg. Instn 24, 59–90 (1933).

    Google Scholar 

  • Lendon, R. G., Forbes, M.: Deformities of the renal tract associated with spina bifida in trypan blue treated rat embryos. J. Anat. (Lond.) 110, 383–391 (1971).

    Google Scholar 

  • Lenz, W.: Der Zeitplan der menschlichen Organogenese als Maßstab für die Beurteilung teratogener Wirkungen. Fortschr. Med. 87, 520–526 (1969).

    Google Scholar 

  • Lovasy, E., Veillon, E.: Dictionnaire des termes d'anatomie, d'embryologie et d'histologie. Paris: Maloine 1954.

    Google Scholar 

  • Ludwig, E.: Über einen operativ gewonnenen menschlichen Embryo mit einem Ursegment (Embryo Da 1). Morph. Jb. 59, 41–104 (1928).

    Google Scholar 

  • Ludwig, E.: Über Frühstadien des menschlichen Ureterbaumes. Acta anat. (Basel) 49, 169–184 (1962).

    Google Scholar 

  • Mall, F. P.: On stages of the development of human embryos from 2 to 25 mm long. Anat. Anz. 46, 78–84 (1914).

    Google Scholar 

  • Marshall, V. F., Muecke, E. C.: Congenital abnormalities of the bladder. In: C. E. Alken, V. W. Dix, W. E. Goodwin, H. M. Weyrauch, and E. Wildbolz (ed.), Handbuch der Urologie, Bd. 7 (1), S. 165–223. Berlin-Heidelberg-New York: Springer 1968.

    Google Scholar 

  • Meyer, J. B.: Die Sulci und Columnae der menschlichen embryonalen Niere und ihre Beziehungen zur Ureterverzweigung. Acta anat. (Basel) 73, 534–568 (1969).

    Google Scholar 

  • Muecke, E. C.: The role of the cloacal membrane in exstrophy. The first successful experimental study. J. Urol. (Baltimore) 92, 659–667 (1964).

    Google Scholar 

  • Olivier, G., Pineau, H.: Horizons de Streeter et âge embryonnaire. Bull. Ass. Anat. 47, 573–576 (1962).

    Google Scholar 

  • O'Rahilly, R.: The timing and sequence of events in human cardiogenesis. Acta anat. (Basel) 79, 70–75 (1971).

    Google Scholar 

  • O'Rahilly, R.: Developmental stages in human embryos. Washington, D. C.: Carnegie Institution 1972 (awaiting publication).

  • O'Rahilly, R., Gardner, E.: The timing and sequence of events in the development of the human nervous system. Z. Anat. Entwickl.-Gesch. 134, 1–12 (1971).

    Google Scholar 

  • Payne, F.: General description of a 7-somite human embryo. Contr. Embryol. Carneg. Instn 16, 115–124 (1925).

    Google Scholar 

  • Pillet, J.: Reconstruction des organes pelviens d'embryons humains de 12,5 et de 25 mm. Bull. Ass. Anat. 51, 819–827 (1966).

    Google Scholar 

  • Pohlman, A. G.: The development of the cloaca in human embryos. Amer. J. Anat. 12, 1–26 (1911).

    Google Scholar 

  • Politzer, G.: Die Entwicklung des Wolffschen Ganges beim Menschen. Acta anat. (Basel) 18, 343–360 (1953).

    Google Scholar 

  • Roberts, J. B. M.: Congenital anomalies of the urinary tract and their association with spina bifida. Brit. J. Urol. 33, 309–315 (1961).

    Google Scholar 

  • Rosenquist, G. C.: The origin and movement of nephrogenic cells in the chick embryo as determined by radioautogrpahic mapping. J. Embryol. exp. Morph. 24, 367–380 (1970).

    Google Scholar 

  • Shikinami J: Detailed form of the Wolffian body in human embryos of the first eight weeks. Contr. Embryol. Carneg. Instn 18, 46–61 (1926).

    Google Scholar 

  • Silverman, H.: Über die Entwicklung der Epithelplatten in den Corpuscula renalia der menschlichen Urinere. Acta anat. (Basel) 74, 36–43 (1969).

    Google Scholar 

  • Skinner, H. A.: The origin of medical terms, second edit. Baltimore: Williams and Wilkins 1961.

    Google Scholar 

  • Spaulding, M. H.: The development of the external genitalia in the human embryo. Contr. Embryol. Carneg. Instn 13, 67–88 (1921).

    Google Scholar 

  • Starkenstein, W.: Über die Anlage und die Wanderung der Nachniere beim Menschen. Morph. Jb. 81, 8–20 (1938).

    Google Scholar 

  • Streeter, G. L.: Development of the auricle in the human embryo. Contr. Embryol. Carneg. Instn 14, 111–138 (1922).

    Google Scholar 

  • Streeter, G. L.: Developmental horizons in human embryos. Description of age group XI, 13 to 20 somites, and age group XII, 21 to 29 somites. Contr. Embryol. Carneg. Instn 30, 211–245 (1942).

    Google Scholar 

  • Streeter, G. L.: Developmental horizons in human embryos. Description of age group XIII, embryos about 4 or 5 millimeters long, and age group XIV, period of indentation of the lens vesicle. Contr. Embryol. Carneg. Instn 31, 27–63 (1945).

    Google Scholar 

  • Streeter, G. L.: Developmental horizons in human embryos. Description of age groups XV, XVI, XVII, and XVIII, being the third issue of a survey of the Carnegie Collection. Contr. Embryol. Carneg. Instn 32, 133–203 (1948).

    Google Scholar 

  • Streeter, G. L. (prepared for publication by C. H. Heuser and G. W. Corner): Developmental horizons in human embryos. Description of age groups XIX, XX, XXI, XXII, and XXIII, being the fifth issue of a survey of the Carnegie Collection. Contr. Embryol. Carneg. Instn 34, 165–196 (1951).

    Google Scholar 

  • Torrey, T. W.: The early development of the human nephros. Contr. Embryol. Carneg. Instn 35, 175–197 (1954).

    Google Scholar 

  • Vogl, E.: Rudimente des branchialen Cöloms bei einem menschlichen Embryo. Z. Anat. Entwickl.-Gesch. 77, 226–233 (1925).

    Google Scholar 

  • Wells, L. J.: Development of the human diaphragm and pleural sacs. Contr. Embryol. Carneg. Instn 35, 107–134 (1954).

    Google Scholar 

  • Williams, D. I.: The development of the trigone of the bladder. Brit. J. Urol. 23, 123–128 (1951).

    Google Scholar 

  • Winiwarter, H. von: La constitution et l'involution du corps de Wolff et le développement du canal de Müller dans l'espèce humaine. Arch. Biol. (Liège) 25, 169–268 (1910).

    Google Scholar 

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Authors and Affiliations

  1. Department of Embryology, Carnegie Institution of Washington, Baltimore

    Ronan O'Rahilly & Edward C. Muecke

  2. Department of Anatomy, Wayne State University, Detroit

    Ronan O'Rahilly & Edward C. Muecke

  3. Division of Urology, Department of Surgery, the New York Hospital-Cornell Medical Center, New York

    Ronan O'Rahilly & Edward C. Muecke

Authors
  1. Ronan O'Rahilly
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  2. Edward C. Muecke
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Supported in part by National Institutes of Health (U.S.A.) General Research Support Grant, School of Medicine, Wayne State University.

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O'Rahilly, R., Muecke, E.C. The timing and sequence of events in the development of the human urinary system during the embryonic period proper. Z. Anat. Entwickl. Gesch. 138, 99–109 (1972). https://doi.org/10.1007/BF00519927

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  • DOI: https://doi.org/10.1007/BF00519927

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