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Synthesis and nitrosation of 3- and 3,5-substituted hydantoins

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The cyclization of N-alkylated (arylated) α-ureidocarboxylic acids gives a series of 3-mono- and 3,5-disubstituted hydantoins, and nitrosation of the latter yields their nitroso derivatives. The rotational isomerism of 3-(α-naphthyl)hydantoins has been studied by PMR spectroscopy.

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Literature cited

  1. V. V. Lutsenko, R. A. Blyum, and I. L. Knunyants, Zh. Org. Khim., 7, 1152 (1971).

    Google Scholar 

  2. V. V. Lutsenko, Z. A. Stumbryavichyute, and Z. L. Zhimantene, Zh. Org. Khim., 14, 1203 (1978).

    Google Scholar 

  3. R. S. Baltrushis, Z.-I. G. Beresnyavichyus, I. M. Vizgaitis, and Yu. V. Gatilov, Khim. Geterotsikl. Soedin., No. 12, 1669 (1981).

    Google Scholar 

  4. V. F. Bystrov, Usp. Khim., 41, 512 (1972).

    Google Scholar 

  5. H. Fujiwara and J. M. van der Veen, J. Chem. Soc., Perkin Trans. II, No. 5, 659 (1979).

    Google Scholar 

  6. R. E. Cassady and S. W. Hawkinson, Acta Crystallogr., 38B, 1646 (1982).

    Google Scholar 

  7. L. D. Colebrook, H. G. Giles, A. Granata, S. Icli, and J. R. Fehlner, Can. J. Chem., 51, 3635 (1973).

    Google Scholar 

  8. L. D. Colebrook, S. Icli, and F. H. Hund, Can. J. Chem., 53, 1556 (1975).

    Google Scholar 

  9. W. E. Bentz, L. D. Colebrook, J. R. Fehlner, and A. Rosowsky, Chem. Commun., No. 16, 974 (1970).

    Google Scholar 

  10. V. V. Lutsenko, Zh. Org. Khim., 15, 1973 (1979).

    Google Scholar 

  11. K.-A. V. Klimavichyus, R. A. Blyum, V. I. Shimkyavichene, Ya. V. Valavichene, and V. V. Lutsenko, in: Proceedings of the All-Union Conference on Timely Problems in the Experimental Chemotherapy of Tumors [in Russian], Chernogolovka (1980), p. 43.

  12. H. Aspelund, Acata Acad. Aboensis, Math. Phys., No. 23, 2 (1962).

    Google Scholar 

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Authors and Affiliations

  1. Institute of Biochemistry, Academy of Sciences of the Lithuanian SSR, 232021, Vil'nyus

    K. -A. V. Klimavichyus, V. V. Lutsenko, G. V. Paulauskaite, P. P. Mikul'skis, G. A. Bal'chitis & S. L. Ionushauskas

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  1. K. -A. V. Klimavichyus
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  2. V. V. Lutsenko
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  3. G. V. Paulauskaite
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  4. P. P. Mikul'skis
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  5. G. A. Bal'chitis
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  6. S. L. Ionushauskas
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1404–1406, October,

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1404–1406, October,

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Klimavichyus, K.A.V., Lutsenko, V.V., Paulauskaite, G.V. et al. Synthesis and nitrosation of 3- and 3,5-substituted hydantoins. Chem Heterocycl Compd 20, 1160–1162 (1984). https://doi.org/10.1007/BF00503612

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  • DOI: https://doi.org/10.1007/BF00503612

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