Abstract
Pulmonary edema and hydrothorax were observed in mature swine that died approximately 5 days after consuming corn screenings. These postmortem observations were reproduced in younger pigs that died within 1 week when fed the corn screenings under experimental conditions. Additionally, pulmonary edema and hydrothorax were induced in a pig that died after receiving 4 daily intravenous injections of fumonisin B1, a toxic metabolite produced by Fusarium moniliforme.
Similar content being viewed by others
References
Kriek NPJ, Kellerman TS, Marasas WFO. Comparative study of the toxicity of Fusarium verticilloides (= Fusarium moniliforme) to horses, primates, pigs, sheep and rats. Onderstepoort J Vet Res 1981; 48: 129–31.
Kriek NPJ, Marasas WFO, Thiel PG. Hepato- and cardi-otoxicity of Fusarium verticillioides (F. moniliforme) isolates from southern african maize. Fd. Chem Toxicol 1981; 19: 447–56.
Bezuidenhout SC, Gelderblom WCA, Gorst-Allman CP, Hoak RM, Marasas WFO, Spiteller G, Vleggaar R. Structure elucidation of the fumonisins, mycotoxins from Fusarium moniliforme. J Chem Soc, Chem Commun 1988; 743–5.
Sydenham EW, Wentzel CA, Gelderblom WCA, Theil PG, Marasas WFO. Evidence for the natural occurance of fumonisin B1, a mycotoxin produced by Fusarium moniliforme in corn. J Agric Food Chem 1990; 38: 285–90.
Wilson TM, Ross PF, Rice LG, Osweiler GD, Nelson HA, Owens DL, Plattner RD, Reggiardo C, Noon TH, Picknell JW. Fumonisin B1 levels associated with an epizootic of equine leukoencephalomalacia. J Vet Diagn Invest 1990; 2: 213–6.
Kellerman TS, Marasas WFO, Thiel PG, Gelderblom WCA, Cawood M, Coetzer JAW. Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B1. Onderstepoort J Vet Res 1991; 57: 269–76.
Ross PF, Rice LG, Plattner RD, Osweiler GD, Wilson TM, Owens DL, Nelson HA, Richards JL. Concentrations of fumonisin B1 in feeds associated with animal health problems. Mycopathologia 1991; 114: 129–135.
Ross PF, Rice LG, Reagon JC, Osweiler GD, Wilson TM, Nelson HA, Owens DL, Plattner RD, Harlin KA, Richards JL, Colvin BM, Benton MI. Fumonisin B1 concentrations of feeds from 45 confirmed equine leukoencephalomalacia cases. J Vet Diagn Invest 1991; 3: 238–241.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Colvin, B.M., Harrison, L.R. Fumonisin-induced pulmonary edema and hydrothorax in swine. Mycopathologia 117, 79–82 (1992). https://doi.org/10.1007/BF00497282
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00497282