Summary
150 human arterial segments of high or low susceptibility to develop atheromas were studied for differences in the amount of histochemically demonstrable acid esterase in them. An inverse relationship was found between intimal or medial enzyme content and susceptibility to atheroma formation.
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Gaton, E., Bubis, J.J., Wolman, M.: Acid esterase in the aorta of the hyperlipidemic rat: a histochemical study. Path. europ. 10, 129–133 (1975)
Holt, S.J., Withers, R.F.J.: Studies in enzyme cytochemistry. V. An appraisal of indigogenic reactions for esterase localization. Proc. roy. Soc. London B 148, 520–532 (1958)
Holt, S.J.: Some observation on the occurrence and nature of esterase in lysosomes. In: Ciba Foundation Symposium on Lysosomes, pp. 114–120. London: J. & A Churchill 1963
Lake, B.D.: Histochemical detection of the enzyme deficiency in blood films in Wolman's disease. J. clin. Path. 24, 617–620 (1971)
Lake, B.D., Patrick, A.D.: Wolman's disease: Deficiency of E600-resistant acid estrase activity with storage of lipids in lysosomes. J. Pediat. 76, 262–266 (1970)
Parker, F.: An electron microscopic study of experimental atherosclerosis. Amer. J. Path. 36, 19–53 (1960)
Pearse, A.G.E.: Naphthyl acetate methods for esterase. HPR. Method. In: Histochemistry, theoretical and applied, Ed. 3, Vol. 2, p. 1303. Edinburgh and London: Churchill Livingstone 1972
Sloan, H.R., Fredrickson, D.S.: Enzyme deficiency in cholesteryl ester storage disease. J. clin. Invest. 51, 1923–1926 (1972)
Wolman, M.: Acid esterase as a factor in atheromatosis. Atherosclerosis 20, 217–223 (1974)
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Barbey, S., Borit, A. Acid esterase in human arteries. Histochemistry 49, 37–41 (1976). https://doi.org/10.1007/BF00490124
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DOI: https://doi.org/10.1007/BF00490124