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Kidney esterases of Mus musculus: Further polymorphism of esterase-6, esterase-9, and a new esterase, esterase-20

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Abstract

The comparison of results obtained by different separation and staining techniques permits the definition of esterase-6 in comparison with esterase-9 and a new esterase, esterase-20. Alleles of Es-6 affect the product's ability to aggregate. Esterase-20 may be an aggregated product of Es-9. The close linkage of Es-6 and Es-9 is confirmed. Homology of esterase-6 with esterases from other mammalian species is also suggested.

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References

  • Arndt, R., Heymann, E., Junge, W., Krisch, K., and Hollandt, H. (1973). Reinigung und molekulare Eigenschaften einer unspezifischen Carboxylesterase (E1) aus Lebermikrosomen der Ratte. Eur. J. Biochem. 36120.

    Google Scholar 

  • Barker, D. L., and Jencks, W. P. (1969). Pig liver esterase. Physical properties. Biochemistry 83879.

    Google Scholar 

  • Böcking, A., Hansert, J., and von Deimling, O. (1976). Esterase XXII. Cellular and sub-cellular localisation of the Es-9 esterase in mouse kidney. Histochemistry 46177.

    Google Scholar 

  • Cobbs, G. (1976). Polymorphism for dimerising ability at the esterase-5 locus in Drosophila pseudoobscura. Genetics 8253.

    Google Scholar 

  • Cortner, J. A., and Schnatz, J. D. (1967). Electrophoretic behavior of alkaline lipolyptic activity in human adipose tissue. Biochim. Biophys. Acta 139107.

    Google Scholar 

  • Cortner, J. A., and Schnatz, J. D. (1970). Alkaline lipolytic activity of rabbit adipose tissue: Genotypes and their inheritance. biochem. Genet. 4529.

    Google Scholar 

  • Gomori, G. (1952). Histochemistry of esterase. Int. Rev. Cytol. 1323.

    Google Scholar 

  • Göppinger, A., Riebschläger, M., Ronai, A., and von Deimling, O. (1978). Esterase XXVIII. Purification and characterization of esterase-9A of mouse kidney. Biochim. Biophys. Acta 52574.

    Google Scholar 

  • Hedrik, J., and Smith, A. J. (1968). Size and charge isomer separation and estimation of molecular weights of proteins by disc gel electrophoresis. Arch Biochem. Biophys. 126155.

    Google Scholar 

  • Hermes, B., Riebschläger, M., and von Deimling, O. (1975). Esterase. XX. Diskelectrophoretische Untersuchungen zum Polymorphismus der Esterasen der Hausmaus. Histochemistry 4381.

    Google Scholar 

  • Heymann, E., and Junge, W. (1979). Characterization of the isozymes of pig liver esterase. I. Chemical studies. Eur. J. Biochem. 95509.

    Google Scholar 

  • Holt, S. J. (1958). Indigogenic staining methods for esterases. In Danielli, J. F. (ed.), General Cytological Methods, Vol. I Academic Press, New York, p. 375.

    Google Scholar 

  • Junge, W., Krisch, K., and Hollandt, H. (1974). Further investigations on the subunit structure of microsomal carboxylesterases from pig and ox livers. Eur. J. Biochem. 43379.

    Google Scholar 

  • Lipps, A., Ronai, A., and von Deimling, O. (1979). Esterase-7, a common constituent of numerous mouse tissues. Comp. Biochem. Physiol. 62B201.

    Google Scholar 

  • Maurer, H. R. (1971). Disc Electrophoresis and Related Techniques of Polyacrylamide Gel Electrophoresis. 2nd ed. Walter de Cruyter, Berlin-New York.

    Google Scholar 

  • Mentlein, R., Heiland, S., and Heymann, E. (1980). Simultaneous purification and comparative characterization of six serine hydrolases from rat liver microsomes. Arch. Biochem. Biophys. 200547.

    Google Scholar 

  • Peters, J., and Nash, H. R. (1977). Polymorphism of esterase-11 in Mus musculus, a further esterase locus on chromosome-8. Biochem. Genet. 15217.

    Google Scholar 

  • Peters, J., and Nash, H. R. (1978). Esterases of Mus musculus: Substrate and inhibition characteristics, new isozymes, and homologies with man. Biochem. Genet. 16553.

    Google Scholar 

  • Petras, M. L., and Sinclair, P. (1969). Another esterase variant in the kidney of the house mouse, Mus musculus. Can. J. Genet. Cytol. 1197.

    Google Scholar 

  • Rothe, G. M. (1980). A survey of the formation and localization of secondary isozymes in mammalia. Hum. Genet. 56129.

    Google Scholar 

  • Ruddle, F. H., and Harrington, L. (1967). Tissue specific esterase isozymes of the mouse (Mus musculus). Exp. Zool. 16651.

    Google Scholar 

  • Schollen, J., Bender, K., and von Deimling, O. (1975). Esterase. XXI. Es-9, a possibly new polymorphic esterase in Mus musculus genetically linked to Es-2. Biochem. Genet. 13369.

    Google Scholar 

  • Wienker, T., Forsgren, K., and von Deimling, O. (1973). Esterase. XI. Histochemische, electrophoretische und quantitative Befunde zum geschlechtsspezifischen Substratspaltmuster der unspezifischen Nierenesterase der Maus. Histochemie 37275.

    Google Scholar 

  • Womack, J. E. (1975). Esterase-6 (Es-6) in laboratory mice: Hormone-influenced expression and linkage relationship to Oligosyndactylism (Os), Esterase-1 (Es-1) and Esterase-2 (Es-2) in chromosome-8. Biochem. Genet. 13311.

    Google Scholar 

  • Womack, J. E., and Sharp, M. (1976). Comparative autosomal linkage in mammals: Genetics of esterases in Mus musculus and Rattus norvegicus. Genetics 82665.

    Google Scholar 

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HRN was supported by the Medical Research Council. This is communication No. 32 of a research program devoted to the cellular distribution, genetics, and regulation of nonspecific esterases.

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Nash, H.R., von Deimling, O. Kidney esterases of Mus musculus: Further polymorphism of esterase-6, esterase-9, and a new esterase, esterase-20. Biochem Genet 20, 537–554 (1982). https://doi.org/10.1007/BF00484703

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  • DOI: https://doi.org/10.1007/BF00484703

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