Abstract
Est-2 and Est-3 linkage disequilibrium was investigated in 43 natural populations. An association between Est-2 0.64 and Est-3 A alleles (or its reverse, Est-3 Null and alleles other than Est-2 0.64) was not observed in 19 (1.2%) of the 1599 mosquitoes analyzed, whereas it should have been found in nearly 400 (25%) individuals if the two loci were in equilibrium. This observation is discussed in relation to organophosphate resistance and genetic distance of the two genes.
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Pasteur, N., Sinègre, G. & Gabinaud, A. Est-2 and Est-3 polymorphisms in Culex pipiens L. from southern France in relation to organophosphate resistance. Biochem Genet 19, 499–508 (1981). https://doi.org/10.1007/BF00484622
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DOI: https://doi.org/10.1007/BF00484622