Abstract
Glutamate-oxaloacetate transaminase (GOT; EC 2.6.1.1) occurs as two electrophoretically distinguishable isozymes in the copepod Tigriopus californicus. The slower-migrating form, referred to as GOT2, is shown to be associated with the mitochondrial cell fraction. GOT2 phenotypes are inherited in typical Mendelian fashion, indicating that they are encoded by a nuclear gene. Allelic frequencies for electrophoretic variants of the two Got loci in 12 California populations of T. californicus show a sharp differentiation of local populations. Linkage studies demonstrated that Got-2 is linked to Got-1; a map of four loci in linkage group I is presented.
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This work was supported by NSF grant DEB-8207000 to R.S.B. and an NIH traineeship in Genetics to M.M.D.
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Dill, M.M., Burton, R.S. Genetics of mitochondrial glutamate-oxaloacetate transaminase (GOT-2) in Tigriopus californicus . Biochem Genet 22, 339–347 (1984). https://doi.org/10.1007/BF00484232
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DOI: https://doi.org/10.1007/BF00484232