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Idiopathic facial palsy

Viral, hereditary, or both?

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Summary

Two cases of acute peripheral facial paralysis occurring in two siblings in a family of six members, who all developed influenza-like symptoms, are reported. Both patients with facial paralysis, as well as two other members of the family had elevated titers against herpes simplex virus, even though it was not possible to demonstrate any raise in titers between the acute and convalescent phase. The “epidemic” occurrence is from a statistical point of view more than just a coincidence, and it is concluded that these findings support the hypothesis that Bell's palsy may be caused by reactivation of herpes simplex virus, probably facilitated by some hereditary component. The authors suggest that a combination of infectious (most likely viral) and hereditary factors may be etiologically important for the occurrence of acute peripheral facial paralysis.

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References

  • Adour, K. K., Bell, D. N., Hilsinger, R. L.: Herpes simplex virus in idiopathic facial paralysis (Bell's palsy). JAMA 233, 527–530 (1975)

    Google Scholar 

  • Adour, K. K.: Cranial polyneuritis and Bell's palsy. Arch. Otolaryngol. 102, 262–264 (1976)

    Google Scholar 

  • Adour, K. K., Byl, F. M., Hilsinger, R. L., Kahn, Z. M., Sheldon, M. I.: The true nature of Bell's palsy: Analysis of 1.000 consecutive patients. Laryngoscope 88, 787–801 (1978)

    Google Scholar 

  • Aitken, R. S., Brain, R. T.: Facial palsy and infection with zoster virus. Lancet 244, 19–22 (1933)

    Google Scholar 

  • DeSanto, L. W., Schubert, H. A.: Bell's palsy, ten cases in a family. Arch. Otolaryngol. 89, 700–702 (1969)

    Google Scholar 

  • Djupesland, G., Berdal, P., Johannessen, T. A., Degré, M., Stien, R., Skrede, S.: The role of viral infection in acute peripheral facial palsy. Acta Otolaryngol. (Stockh.) 79, 221–227 (1975)

    Google Scholar 

  • Djupesland, G., Berdal, P., Johannessen, T. A.: Viral infection as a cause of acute peripheral facial palsy. Arch. Otolaryngol. 102, 403–406 (1976)

    Google Scholar 

  • Djupesland, G., Degré, M., Stien, R., Skrede, S.: Acute peripheral facial palsy. Part of a cranial polyneuropathy? Arch. Otolaryngol. 103, 641–644 (1977)

    Google Scholar 

  • Hunt, J. R.: The sensory system of the facial nerve and its symptomatology. J. Nerv. Ment. Dis. 36, 321–350 (1909)

    Google Scholar 

  • Leibowitz, U.: Epidemic incidence of Bell's palsy. Brain 92, 109–114 (1969)

    Google Scholar 

  • Lewis, G. W.: Zoster sine herpete. Br. Med. J. 1958 II, 418–421

    Google Scholar 

  • Peitersen, E., Caunt, E. E.: The incidence of herpes zoster antibodies in patients with peripheral facial palsy. J. Laryngol. Otol. 84, 65–70 (1970)

    Google Scholar 

  • Tomita, H., Hayakawa, W., Hondo, R.: Varicella-zoster virus in idiopathic facial palsy. Arch. Otolaryngol. 95, 364–368 (1972)

    Google Scholar 

  • Willbrand, J. W., Blumhagen, J. D., May, M.: Inherited Bell's palsy. Ann. Otol. Rhinol. Laryngol. 83, 343–346 (1974)

    Google Scholar 

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Thomsen, J., Barfoed, C. Idiopathic facial palsy. Arch Otorhinolaryngol 222, 109–112 (1979). https://doi.org/10.1007/BF00469749

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  • DOI: https://doi.org/10.1007/BF00469749

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