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Proposed routine method for phenotyping of cholinesterase (CHE) locus E1 variants with butyrylthiocholine as substrate at 37 °C

Vorschlag für ein Routine-Verfahren zur Bestimmung der Locus E1 Phaenotypen der Cholinesterase (CHE)-Varianten mit Butyrylthiocholin als Substrat bei 37 ° C

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Conclusion

The proposed method is based on routine reagents and equipment, and gives reliable results. The three inhibitors are suited to decide, if a low CHE activity is inherited or acquired and to estimate the degree of succinylcholine sensitivity of its carrier.

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References

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Authors and Affiliations

  1. Abteilung Gastroenterologie und Hepatologie im Zentrum Innere Medizin und Dermatologie, Medizinische Hochschule, D-3000, Hannover 61, Federal Republic of Germany

    E. Schmidt, R. Klaukc & F. W. Schmidt

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  1. E. Schmidt
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  2. R. Klaukc
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  3. F. W. Schmidt
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Schmidt, E., Klaukc, R. & Schmidt, F.W. Proposed routine method for phenotyping of cholinesterase (CHE) locus E1 variants with butyrylthiocholine as substrate at 37 °C. Z. Anal. Chem. 330, 364 (1988). https://doi.org/10.1007/BF00469286

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  • DOI: https://doi.org/10.1007/BF00469286

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