Zusammenfassung
Die Innenohrflüssigkeiten von Meerschweinchen und Katzen wurden auf den Gehalt von Na, K, Chlorverbindungen, Glukose und Gesamtprotein untersucht, um artspezifische Unterschiede festzustellen. In der Perilymphe von Scala tympani und Scala vestibuli sind Na, K, Chloride und Gesamtprotein beim Meerschweinchen geringer als bei der Katze. Dagegen zeigt die Perilymphe des Meerschweinchens einen höheren Glukosegehalt als die der Katze. Die Endolymphe des Utriculus enthält beim Meerschweinchen mehr Na und weniger K als bei der Katze. Die Resultate sind wichtig für phylogenetische Untersuchungen der Biochemie der Innenohrflüssigkeiten.
Summary
Inner ear fluids of guinea pigs and cats were analyzed for sodium, potassium, chloride, glucose, and total protein to determine species differences in chemical compositions. In the scala vestibuli perilymph and scala tympani perilymph, sodium, potassium, and choride levels in the guinea pig were lower than in the cat. The protein levels in the scala vestibuli perilymph and scala tympani perilymph of the guinea pig were lower than those of the cat. The glucose levels in the guinea pig were higher in the scala vestibuli perilymph and scala tympani perilymph, as compared to findings in the cat. Regarding the utricular endolymph, there were significant differences between guinea pigs and cats in sodium and potassium concentrations; the concentration in the former being higher in sodium and lower in potassium. These findings are pertinent for the phylogenetic studies on inner ear fluid biochemistry.
This is a preview of subscription content, log in via an institution to check access.
References
Amoore JE, Rodgers K, Young JZ (1959) Sodium and potassium in the endolymph and perilymph of the statocyst and the eye of the octopus. J Exp Biol 36:709–714
Enger PS (1964) Ionic composition of the cranial and labyrinthine fluids and saccular DC potentials in fish. Comp Biochem Physiol 11:131–137
Hashimoto K, Nukata S (1951) Cardiac metabolism (111). Folia Pharm Japon 47:9–10
Jensen CE, Vilstrup T (1954) Determination of some inorganic substances in the labyrinthine fluids. Acta Chem 8:697–698
Johnstone BM, Sellick PM (1972) The peripheral auditory apparatus. Q Rev Biophys 5:1–57
Kuijpers W, Bouting SL (1970a) The cochlear potentials 1. The effect of oubain on the cochlear potentials of the guinea pig. Pflügers Arch 320:348–358
Kuijpers W, Bouting SL (1970b) The cochlear potentials 11. The nature of the cochlear endolymphatic resting potential. Pflügers Arch 320:359–372
Lowry OH, Rosebrough NJ, Farr AL, Randoll RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–275
Makimoto K, Silverstein H (1974a) Sodium and potassium concentrations in the endolymph and perilymph of the cat. Ann Otol 83:174–179
Makimoto K, Silverstein H (1974b) Effects of insulin on glucose concentrations in inner ear fluids and cochlear microphonics. Laryngoscope 84:722–737
Makimoto K, Takeda T, Silverstein H (1978) Chemical composition in various compartments of inner ear fluid. Arch Otorhinolaryngol 220:259–264
Murray RW, Potts WTW (1961) The composition of the endolymph, perilymph and other body fluids of elasmobranches. Comp Biochem Physiol 2:65–75
Murty VN, Kehar ND (1951) Physiological studies on the blood of domestic animals. II Goats. Indian J Physiol 5:71–78
Silverstein H (1973) Inner ear fluids in man. Laryngoscope 83:79–107
Somogyi M (1933) The distribution of sugar and rate of glucolysis in the blood of some mammals. J Biol Chem 103:665–670
Author information
Authors and Affiliations
Additional information
This work was supported by Research Grant No. ROI-NS1026801 from the National Institute of Neurological Diseases and Strokes, USA
Rights and permissions
About this article
Cite this article
Makimoto, K., Takeda, T. & Silverstein, H. Species differences in inner ear fluids. Arch Otorhinolaryngol 228, 187–193 (1980). https://doi.org/10.1007/BF00454226
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00454226