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Verteilungsmuster von Histokompatibilitätsantigenen (HLA) bei Nasopharynxtumoren

The spectrum of histocompatibility antigens (HLA) in tumors of the nasopharynx

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Summary

HLA typing in 20 patients with tumors of the nasopharynx showed no significantly increased frequency of HLA A2, BW46 (Sin2), and B5 as demonstrated by other authors. In our investigations, we found no particular HLA antigen as a genetic marker for nasopharyngeal tumors in the population of middle and northern Europe.

Zusammenfassung

Bei 20 Patienten mit Nasopharynxtumoren wurden die HLA-ABC-Antigene bestimmt. Die von anderen Autoren mitgeteilten Erhöhungen der HLA-Antigene A2, BW46 (Sin2) und B5 konnten nicht bestätigt werden. Somit ist nach unseren Untersuchungen in Mittel- und Nordeuropa kein spezielles HLA-ABC-Antigen als genetischer Marker für Nasopharynxtumoren zu finden.

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Literatur

  1. Betuel H, Camoun M, Colombani, Day NE, Ellouz R, De-Thé G (1975) The relationship between nasopharnygeal carcinoma and the HL-A system among tunisians. Int J Cancer 16: 249

    Google Scholar 

  2. Chan SH, Day NE, Khor TH, Chia KB, Kunaratnam N (1981) HLA markers in the development and prognosis of NPC in Chinese. In: Grundmann et al. (eds) Cancer campaign, vol 5: Nasopharyngeal carcinoma. Fischer, Stuttgart New York, p 205

    Google Scholar 

  3. Dausset J, Svejgard A (1977) HLA and disease. Munksgaard Kopenhagen/North and South America: Williams and Wilkins, Baltimore

    Google Scholar 

  4. Krüger J, Ieromnimon V, Dahr W (1981) Frequencies of HLA antigens in patients with NPC. In: Grundmann et al. (eds) Cancer campaign, vol 5: Nasopharyngeal carcinoma. Fischer, Stuttgart New York, p 201

    Google Scholar 

  5. Simons MJ, Chan SH, Wee GB, Day NE, De-Thé GB (1975) Probable identification of an HL-A second-locus antigen associated with a high risk of nasopharyngeal carcinoma. Lancet 1: 142

    Google Scholar 

  6. Simons MJ, Chan SH, Darmalingam S, Wee GB, Shanmugaratnam K, Prasad U, Goh EH, Betuel H, Ho JHC, Chau JCW, Day NE, De-Thé G (1978) Nasopharyngeal carcinoma and histocompatibility antigens. In: Simons MJ (ed) International Agency for Research on Cancer Scientific Publication 20: 271

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Authors and Affiliations

  1. Abteilung für Hals-Nasen-Ohrenkrankheiten, Klinik und Poliklinik für Hals-Nasen-Ohrenkrankheiten, Klinikum der Christian-Albrechts-Universität, Hospitalstraße 20, D-2300, Kiel, Bundesrepublik Deutschland

    A. Beigel & J. F. Peulen

  2. Abteilung Immunologie, Klinikum der Christian-Albrechts-Universität, D-2300, Kiel

    E. Westphal

Authors
  1. A. Beigel
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  2. J. F. Peulen
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  3. E. Westphal
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Additional information

Auszugsweise vorgetragen vor der 66. Versammlung der Vereinigung Südwestdeutscher Hals-Nasen-Ohrenärzte, 24.–26. September 1982, Ulm

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Beigel, A., Peulen, J.F. & Westphal, E. Verteilungsmuster von Histokompatibilitätsantigenen (HLA) bei Nasopharynxtumoren. Arch Otorhinolaryngol 237, 285–288 (1983). https://doi.org/10.1007/BF00453734

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  • DOI: https://doi.org/10.1007/BF00453734

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