Abstract
Haloperidol serum concentrations were determined after IM or oral treatment in 15 schizophrenic patients. No correlation was found between drug levels and therapeutic effect. However, a good relationship was found between the half-life calculated after the first IM injection and the BPRS decrease after 3 weeks. Therefore a serum level study on the first day may forecast the therapeutic response.
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Moulin, M.A., Davy, J.P., Debruyne, D. et al. Serum level monitoring and therapeutic effect of haloperidol in schizophrenic patients. Psychopharmacology 76, 346–350 (1982). https://doi.org/10.1007/BF00449123
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DOI: https://doi.org/10.1007/BF00449123