Abstract
A 2-year-old girl who presented with blindness, aphasia and inability to move the right arm and leg following a convulsive episode was found to have hypertension, precocious pseudopuberty, features of Cushing syndrome and an ovarian tumour. The hormonal profile suggested an adrenal cortical tumour, which turned out to be lcoated in the ovary and the cause of the ovarian enlargement. Following removal of the mass, all the abnormal features regressed and the blood pressure returned to normal.
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References
Adelman S, Benson C, Hertzler J (1975) Surgical lesions of the ovary in infancy and childhood. Surg Gynecol Obstet 141:219–222
Breen JL, Maxson WS (1977) Ovarian tumors in children and adolescents. Clin Obstet Gynecol 20:607–23
Ein SH (1973) Malignant ovarian tumors in children. J Pediatr Surg 8:539–42
Iverson L (1947) Masculinizing tumors of the ovary: a clinicopathologic survey with discussions of histogenesis and report of 3 cases. Surg Gynecol Obstet 84:213–238
Kepler EJ, Dockerty MB, Priesterley JT (1944) Adrenal-like ovarian tumor associated with Cushing's syndrome. Am J Obstet Gynecol 47:43–62
Metcalf MG (1963) A rapid method for measuring 17-hydroxy-corticosteriods in urine. J Endocrinol 26:415–25
Silber BH, Busch BD (1956) An improved procedure for the determination of hydrocortisone in human plasma. J Clin Endocrinol Metab 16:1333–36
Towne BH, Mahour H, Woolley MM (1975) Ovarian cysts and tumors in infancy and childhood. J Pediatr Surg 10:311–320
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Debo Adeyemi, S., Grange, A.O., Giwa-Osagie, O.F. et al. Adrenal rest tumour of the ovary associated with isosexual precocious pseudopuberty and cushingoid features. Eur J Pediatr 145, 236–238 (1986). https://doi.org/10.1007/BF00446077
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DOI: https://doi.org/10.1007/BF00446077