Abstract
We report a case of chronic human pulmonary sporotrichosis which was not associated with superficial manifestations involving the skin or lymph nodes. As it is difficult to verify an etiology, it is possible that some undiagnosed pulmonary granulomas could represent pulmonary sporotrichosis of the chronic type. These may have been treated for other diseases, such as a mycobacterial infection as in this case. Since the immunodiffusion test is a simple procedure and is almost always positive in chronic disease, its greater utilization should help in defining this disease more frequently. The skin test, agglutination test and culture are variably useful as documented in the literature.
Sporotrichosis is a common mycotic infection which is usually confined to the skin and superficial lymph nodes. In disseminated disease, the lung is very rarely involved. Pulmonary sporotrichosis then represents a second form of primary infection though less common than the lymphocutaneous disease. Scott et al. (18) reported two cases of pulmonary sporotrichosis. Ridgeway et al. (15) at about the same time reviewed the previously reported cases up to 1962 and concluded that 12 of the cases could be accepted as sporotrichosis and added two cases of their own. Subsequently, Siegrist & Ferrington (20) and Trevathan & Phillips (23) each reported a case. Presently, approximately 50 cases have been reported in the United States (1–10, 12, 13, 16). Chronic and acute involvement have been delineated by Ridgeway et al. (15) It is believed that the following case represents one of primary pulmonary sporotrichosis of the chronic type without manifest involvement of other organs.
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References
Baum, G. I., R. I. Donnerberg, D. Stewatt, W. J. Mulligan & L. R. Putnam. 1969. Pulmonary sporotrichosis. N. Engl. J. Med. 280: 410–413.
Beland, J. E., E. Mankiewicz & D. J. MacIntosh. 1968. Primary pulmonary sporotrichosis. Can. Med. Assoc. J. 99: 813–816.
Evers, R. H. & R. R. Whereatt. 1974. Pulmonary sporotrichosis. Chest, 66: 91–92.
Khan, F. A., J. J. Guarneri & M. F. Sierra. 1975. Primary pulmonary sporotrichosis complicated by perirectal abscess. Am. Rev. Respir. Dis. 112: 119–123.
Kobayashi, G. & I. N. Newmark. 1969. Pulmonary sporotrichosis. JAMA 210: 1741–1744.
Lurie, H. I. 1971. Sporotrichosis in Pathologic Anatomy of Mycoses: Human Infection with Fungi Actinomycetes. R. D. Barker, Ed., Springer-Verlag, New York, pp. 614–675.
Lynch, P. J., J. J. Voorhees & F. R. Harrell. 1970. Systemic sporotrichosis. Ann. Intern. Med. 73: 23
McCahn, W. H. & W. I. Buell. 1968. Primary pulmonary sporotrichosis in Illinois. Ill. Med. J. 134: 255–258.
McGavran, M. H., G. Kobayashi, L. Newmark, M. Newberry, C. A. Miller & C. G. Harford. 1969. Pulmonary sporotrichosis. Dis. Chest, 56: 547–549.
Mohr, J. A., C. D. Patterson, B. G. Eaton, F. R. Rhoades & N. Nichols. 1972. Primary pulmonary sporotrichosis. Am. Rev. Respir. Dis. 106: 260–264.
Moore, M. & R. L. Kile. 1935. Generalized subcutaneous gummatous ulcerating sporotrichosis. Report of a case with study of etiologic agent. Arch. Derm. Syph. 31: 672–685.
Parker, J. D., G. A. Sarosi & F. E. Tosh. 1970. Treatment of extracutaneous sporotrichosis. Arch. Intern. Med. 125: 858–863.
Post, G. W., A. Jacksen, P. E. Garber & G. E. Veach. 1958. Primary sporotrichosis. Dis. Chest, 34: 455–459.
Raffel, S. Immunity, IInd Ed., Appleton-Century-Crofts, New York, pp. 160–161.
Ridgeway, N. A., F. C. Witcomb, E. E. Erickson & S. W. Law. 1962. Primary pulmonary sporotrichosis. Report of two cases. Am. J. Med. 32: 153–160.
Roberts, G. D. & H. W. Larsh. 1971. The serologic diagnosis of extracutaneous sporotrichosis. Am. J. Clin. Pathol. 56: 597–600.
Rohwedder, J. J. & G. Archer. 1976. Pulmonary sporotrichosis: treatment with miconazole. Am. Rev. Respir. Dis. 114: 403–406.
Scott, S. M., E. D. Peasley & T. P. Crymes. 1961. Pulmonary sporotrichosis. Report of two cases with cavitation. N. Engl. J. Med. 265: 453–457.
Sethi, K. K., V. L. Kneipp & J. Schwarz. 1966. Pulmonary sporotrichosis in mice following intranasal infection. Am. Rev. Respir. Dis. 93: 463–465.
Siegrist, H. D. & E. Ferrington. 1965. Primary pulmonary sporotrichosis. South. Med. J. 58: 728–735.
Singer J. J. & J. E. Muncie. 1952. Sporotrichosis, etiologic considerations and report of additional cases from New York. N. Y. State J. Med. 52: 2147–2149.
Smith, A. G., W. K. C. Morgan, R. B. Hornick & A. M. Funk. 1970. Chronic pulmonary sporotrichosis. Am. J. Clin. Pathol. 54: 401–409.
Trevathan, R. D. & S. Phillips. 1966. Primary pulmonary sporotrichosis. JAMA 195: 965–967.
Wilson, D. E., J. J. Mann, et al. 1967. Clinical features of extracutaneous sporotrichosis. Medicine (Baltimore) 46: 265–280.
Wilson, J. W. 1961. Therapy of systemic fungus infections in 1971. AMA Arch. Intern. Med. 108: 292–316.
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Zvetina, J.R., Rippon, J.W. & Daum, V. Chronic pulmonary sporotrichosis. Mycopathologia 64, 53–57 (1978). https://doi.org/10.1007/BF00443090
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DOI: https://doi.org/10.1007/BF00443090