Abstract
A 12-year-old boy with aplastic anemia developed severe but reversible cardiac failure after treatment with 200 mg/kg cyclophosphamide (4×50 mg/kg on four consecutive days) given as preparation for bone marrow grafting. This and previously reported cases demonstrate the possibility of cardiotoxicity after high doses of the drug.
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von Bernuth, G., Adam, D., Hofstetter, R. et al. Cyclophosphamide cardiotoxicity. Eur J Pediatr 134, 87–90 (1980). https://doi.org/10.1007/BF00442410
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DOI: https://doi.org/10.1007/BF00442410