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Life-threatening intracranial hypertension in reye's syndrome treated with intravenous thiopentone

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Abstract

A patient with Reye syndrome is described in whom cerebral perfusion pressure was reduced to less than 5 mm Hg with loss of EEG activity. The intravenous administration of thiopentone reduced intracranial pressure and improved cerebral perfusion pressure with restoration of EEG and full recovery.

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Abbreviations

ICP:

intracranial pressure

EEG:

electroencephalograph

CFM:

cerebral function monitor

CPP:

cerebral perfusion pressure

IAP:

intra-arterial pressure

References

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McWilliam, R.C., Stephenson, J.B.P. Life-threatening intracranial hypertension in reye's syndrome treated with intravenous thiopentone. Eur J Pediatr 144, 383–384 (1985). https://doi.org/10.1007/BF00441783

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  • DOI: https://doi.org/10.1007/BF00441783

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