Abstract
A patient with Reye syndrome is described in whom cerebral perfusion pressure was reduced to less than 5 mm Hg with loss of EEG activity. The intravenous administration of thiopentone reduced intracranial pressure and improved cerebral perfusion pressure with restoration of EEG and full recovery.
Similar content being viewed by others
Abbreviations
- ICP:
-
intracranial pressure
- EEG:
-
electroencephalograph
- CFM:
-
cerebral function monitor
- CPP:
-
cerebral perfusion pressure
- IAP:
-
intra-arterial pressure
References
DeVico DC (1983) How common is Reye's syndrome? N Engl J Med 309:179–181
Glasgow JFT (1984) Clinical features and prognosis of Reye's syndrome. Arch Dis Child 59:230–235
Hall S, Bellman M (1984) Reye's syndrome in the British Isles: first annual report of the joint British Paediatric Association and Communicable Disease Surveillance Centre surveillance scheme. Br Med J 288:548–550
Mayer T, Walker ML (1982) Emergeney intracranial pressure monitoring in pediatrics. Clin Pediatr 21:391–396
McWilliam RC, Stephenson JBP (1984) A rapid bedside method for monitoring intracranial pressure. Lancet ii:73–75
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
McWilliam, R.C., Stephenson, J.B.P. Life-threatening intracranial hypertension in reye's syndrome treated with intravenous thiopentone. Eur J Pediatr 144, 383–384 (1985). https://doi.org/10.1007/BF00441783
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00441783