Abstract
The effect of sodium benzoate on mice acutely intoxicated with ammonium acetate has been investigated. Benzoate potentiates ammonia toxicity and increases the blood and brain levels of ammonia in mice. The implications of these findings to the treatment with benzoate of hyperammonemia in man are discussed.
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References
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O'Connor, J.E., Ribelles, M. & Grisolia, S. Potentiation of hyperammonemia by sodium benzoate in animals. A note of caution. Eur J Pediatr 138, 186–187 (1982). https://doi.org/10.1007/BF00441151
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DOI: https://doi.org/10.1007/BF00441151