Abstract
High sensitivity rates to the activity of killer toxins produced by 25 species of yeasts belonging to the genera Candida, Hansenula, Pichia, Rhodotorula, Saccharomyces and Trichosporon have been observed among 112 yeast isolates (25 Cryptococcus neoformans, 29 C. glabrata, 16 C. parapsilosis, 20 C. pseudotropicalis and 22 C. tropicalis). The highest sensitivity has been observed among the C. parapsilosis isolates, the lowest in C. glabrata strains. Genera Pichia and Hansenula proved to have the greatest killer activity. A killer system, formerly used for differentiating C. albicans isolates within the species, proved to be valid as epidemiological marker when applied to 112 strains of pathogenic yeasts.
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Middelbeek, E. J., Hermans, J. M. H., Stumm, C. & Muytjens, H., 1980. High incidence of sensitivity to yeast killer toxin among Candida and Torulopsis isolates of human origin. Antimicrob. Agents Chemother. 17: 350–354.
Oblak, D. L., Rhodes, J. C. & Martin, W. J., 1981. Clinical evaluation of the Automicrobic system yeast biochemical Card for rapid identification of medically important yeasts. J. Clin. Microbiol. 13: 351–355.
Polonelli, L., Morace, G., Barcaioli, B. M. & Cossu, A. L., 1981. Survey on Cryptococcus neoformans diffusion in Italy. L'Igiene Moderna 76: 733–741.
Polonelli, L., Archibusacci, C., Sestito, M. & Morace, G., 1983. Killer system: a simple method for differentiating strains of Candida albicans. J. Clin. Microbiol. 17: 774–780.
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Morace, G., Archibusacci, C., Sestito, M. et al. Strain differentiation of pathogenic yeasts by the killer system. Mycopathologia 84, 81–85 (1984). https://doi.org/10.1007/BF00436517
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DOI: https://doi.org/10.1007/BF00436517