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Behavioral effects of dopamine agonists across the estrous cycle in rats

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Abstract

The effects of apomorphine upon stereotype and bromocriptine upon wheel running and intracranial reward were examined across the estrous cycle of female rats. Apomorphine elicited stereotypy in a dose-related fashion, but stereotypy was not reliably or systematically altered by estrous conditions. On the other hand, wheel running was augmented by bromocriptine in an estrous-specific fashion. Self-stimulation was increased by bromocriptine but this was not related to estrous cyclicity. These findings provide evidence for possible behavioral and motivational specificity of dopamine (DA) receptor-related estrous changes.

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Steiner, M., Katz, R.J. & Carroll, B.J. Behavioral effects of dopamine agonists across the estrous cycle in rats. Psychopharmacology 71, 147–151 (1980). https://doi.org/10.1007/BF00434403

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  • DOI: https://doi.org/10.1007/BF00434403

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