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The Zurich study —A prospective epidemiological study of depressive, neurotic and psychosomatic syndromes

I. Problem, methodology

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Summary

The purpose and methodology of a 4-year longitudinal study based on a cohort aged 20 years are presented. A two-stage procedure was chosen; in 1978, 2201 males and 2346 females, aged 19–20, were examined. This sample was representative of the respective age group in the Canton of Zurich. From high and low-scorers (SCL-90), 292 males and 299 females were randomly selected for interview and for a prospective study. Subsequent investigations were carried out by questionnaires and by a personal interview. The instruments chiefly consisted of a semi-structured interview (SPIKE), a clinical syndrome list (SL), a90-item symptom checklist (SCL-90R), a life-event-inventory, scales measuring coping behavior and dissimulation, and an extensive sociological interview dealing with sociodemographic characteristics and social adjustment.

This paper gives an account of the methodological aspects of the study.

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References

  • Agosti E, Agosti F, Ernst K (1974) Psychisch Kranke in einer Allgemeinpraxis. Schweiz Med Wochenschr 104:322–325

    Google Scholar 

  • Andrews FM, Messenger RC (1973) Multivariate Nominal Scale Analysis. A report on a new analysis technique and a computer program. Survey Research Center. Institute for Social Research. The University of Michigan, Ann Arbor/Michigan

    Google Scholar 

  • Andrews FM, Morgan JN, Sonquist JA, Klem L (1975) Multiple Classification Analysis. A report on a computer program for multiple regression using categorical predictors. Institute for Social Research. The University of Michigan, Ann Arbor/ Michigan (2nd printing)

    Google Scholar 

  • Bebbington P, Hurry J, Tennant C, Sturt E, Wing JK (1981) Epidemiology of mental disorders in Camberwell. Psychol Med 11:561–579

    Google Scholar 

  • Binder J, Angst J (1981) A prospective epidemiological study of depressive, psychosomatic and neurotic disturbances (Switzerland). In: Mednick SA, Baert AE (eds), Phillips Bachmann B (ass ed) Prospective Longitudinal Research. An empirical Basis for the Primary Prevention of Psychosocial Disorders. (Published on behalf of the WHO, Regional Office for Europe) Oxford University Press, Oxford New York Toronto Melbourne, pp 157–160

    Google Scholar 

  • Binder J, Sieber M, Angst J (1979) Verzerrungen bei postalischen Befragungen: das Problem der Nichtantworter. Z exp angewandt Psychol 26:53–71

    Google Scholar 

  • Bischofberger A, Thomaier K (1982) Normierung einer Life-EventSkala. Lic Phil 1, Zürich

    Google Scholar 

  • Brown GW, Davidson S, Harris T, Maclean U, Pollock S, Prudo R (1977) Psychiatric Disorder in London and North Uist. Soc Sci Med 11:367–377

    Google Scholar 

  • Brown GW, Harris T (1982) Fall-Off in the Reporting of Life Events. Soc Psychiatry 17:23–28

    Google Scholar 

  • Busslinger M (1984) Validierung des Fragebogens SPIKE an Patienten der Psychiatrischen Poliklinik. Med Diss (in preparation), Zürich

  • Cooper B, Eastwood MR, Sylph J (1970) Psychiatric morbidity and social adjustment in a general practice population. In: Hare EH, Wing JK (eds) World Psychiat Ass-Roy Med Psychol Ass: Psychiatric epidemiology, proc of the int symposium, Aberdeen 1969. Oxford University Press, pp 299–309

    Google Scholar 

  • Derogatis LR (1977) SCL-90. Administration, Scoring and Procedures Manual-I for the R (revised) version and other instruments of the Psychopathology Rating Scale Series. Johns Hopkins University School of Medicine, Chicago

    Google Scholar 

  • Derogatis LR, Lipman RS, Rickels K, Uhlenhuth EH, Covi L (1974) The Hopkins Symptom Checklist (HSCL): A measure of primary symptom dimensions. In: Pichot P (ed) Psychological Measurements in Psychopharmacology. Mod Probl Pharmacopsychiatry 7. Karger, Basel

    Google Scholar 

  • Dyker GD (1975) Epidemiology of depression in general practice. J Int Med Res [Suppl] (1)

  • Eastwood MR (1970) Psychiatric morbidity and physical state in a general practice population. In: Hare EH, Wing JK (eds) World Psychiat Ass-Roy Med Psychol Ass: Psychiatric epidemiology, proc of the int symposium, Aberdeen 1969. Oxford University Press, pp 291–298

    Google Scholar 

  • Ebnöther D (1980) Norm und Normalität: Überprüfung des Normbereichs sozialen Verhaltens. Lizentiatsarbeit an der Universität Zürich

    Google Scholar 

  • Essen-Möller E (1956) Individual traits and morbidity in a Swedish rural population. Acta Psychiat et Neurolog Scand [Suppl 100], Copenhagen

  • Fahrenberg J, Selg H, Hampel R (1973) Das Freiburger Persönlichkeitsinventar FPI, 2. Aufl. Verlag für Psychologie, Hogrefe CJ, Göttingen

    Google Scholar 

  • Fehr-Suter V (1981) Beschreibung der Lebenssituation chronischschizophrener Patienten im Kanton Aargau. Lic Phil I, Zürich

    Google Scholar 

  • Finlay-Jones RA, Burvill PW (1977) The prevalence of minor psychiatric morbidity in the community. Psychol Med 7:475–489

    Google Scholar 

  • Gastpar M (1981) The problem of diagnosing depressive states in general practice. In: Kielholz P (ed) The general practitioner and his depressed patients. A digest of up-to-date knowledge. Hans Huber, Bern Stuttgart Wien, pp 56–62

    Google Scholar 

  • Geser H, Zbinden E (1970) Einige psychosoziale Korrelate der Hypertonie in einem Industriebetrieb. Z Präv Med 15:303–317

    Google Scholar 

  • Goldberg DP (1973) The Detection of Psychiatric Illness by Questionnaire-A technique for the identification and assessment of non-psychotic psychiatric illness. (Maudsley Monograph 21). Oxford University Press, London New York Toronto

    Google Scholar 

  • Goldberg DP, Cooper B, Eastwood MR, Kedward HB, Shepherd M (1970) A standardized psychiatric interview for use in community surveys. Br J Prev Soc Med 24:18–23

    Google Scholar 

  • Goodman LA (1972) A modified multiple regression approach to the analysis of dichotomous variables. Am Sociol Rev 37:28–46

    Google Scholar 

  • Gurland BJ, Stone AR, Frank JD, Fleiss JL (1972) The Structured and Scaled Interview to Assess Maladjustment (SSIAM). Arch Gen Psychiatr 27:259 ff.

    Google Scholar 

  • Hagnell O (1966) A prospective study of the incidence of mental disorder. Svenska Bokförlaget, Lund

    Google Scholar 

  • Hagnell O, Lanke J, Rorsman B (1982a) Suicide and depression in the male part of the Lundby Study. Changes over time during a 25-year observation period. Neuropsychobiology 8:182–187

    Google Scholar 

  • Hagnell O, Lanke J, Rorsman B, Öjesjö L (1982b) Are we entering an age of melancholy? Depressive illnesses in a prospective epidemiological study over 25 years: The Lundby Study, Sweden. Psychol Med 12:279–289

    Google Scholar 

  • Henderson S, Byrne DG, Duncan-Jones P (1981) Neurosis and the Social Environment. Academic Press, Sydney New York London Toronto San Francisco

    Google Scholar 

  • Hinterhuber H (1982) Epidemiologie psychiatrischer Erkrankungen (Monographie, Forum der Psychiatrie; NF, 13) Ferdinand Enke, Stuttgart

    Google Scholar 

  • Holmes TH, Rahe RH (1967) The social readjustment rating scale. J Psychosom Res 11:213–218

    Google Scholar 

  • Hönmann H, Schepank H (1981) Distribution of Neurotic and Psychosomatic Diseases in West Germany. In: Koptagel-Ilal G (ed) Proceedings of the 13th European Conference on Psychosomatic Research, Istanbul 1980, pp 403–409

  • Hull CH, Nie NH (1981) SPSS Update 7-9. New Procedures and Facilities for Releases 7–9. McGraw-Hill, New York

    Google Scholar 

  • Illes P (1981) Validierung des Fragebogens SPIKE an Diagnosen der Krankengeschichten des Sozialpsychiatrischen Dienstes Oerlikon. Med Diss, Zurich

  • Isele R, Angst J (1982) Life-Events und prdmorbide soziale Beziehungen bei ersterkrankten Schizophrenen. In: Huber G (ed) Endogene Psychosen: Diagnostik, Basissymptome und biologische Parameter. 5. „Weissenauer” Schizophrenie-Symposion, Bonn 1982. Schattauer, Stuttgart New York, pp 43–57

    Google Scholar 

  • Isele R, Angst J (1983) Social Disability in Schizophrenia: The controlled prospective BURGHOELZLI STUDY. 1. Case-Finding, Research-Design, and Characteristics of Samples (in preparation)

  • Jenkins CD, Hurst MW, Rose RM (1979) Life changes. Do people really remember? Arch Gen Psychiatr 36:379–384

    Google Scholar 

  • Kielholz P (1974) Internationale Umfragen zum Thema „Die Behandlung der Depression in der täglichen Praxis„: Ergebnisse der Umfrage in der Schweiz. In: Kielholz P (ed) Die Depression in der täglichen Praxis. Hans Huber, Bern Stuttgart Wien, pp 150–151

    Google Scholar 

  • Kielholz P, Ladewig D, Hauswirth R (1979) Psychische Störungen in der täglichen Praxis-Ein Beitrag zur medizinischen Psychologie der Arzt-Patient-Beziehung. Schweiz Rundsch Med (Praxis) 68:1378–1382

    Google Scholar 

  • Kluegel JR (1978) The cause and cost of racial exclusion from job authority. Am Soc Rev 43:285–301

    Google Scholar 

  • Kruskal JB, Young FW, Seery JB (1978) How to use KYST-2A, a very flexible program to do multidimensional scaling and unfolding (extensions by Stassen HH). Bell Laboratories, Murray Hills

    Google Scholar 

  • Leighton AH (1959) My name is legion: Foundations for a theory of man in relation to culture. Basic Books, New York

    Google Scholar 

  • Malzacher M, Merz J, Ebnöther D (1981) Einschneidende Lebensereignisse im Vorfeld akuter schizophrener Episoden. Arch Psychiat Nervenkr 230:227–242

    Google Scholar 

  • Meier A (1984) Validierung des Depressionsratings am Fragebogen SPIKE an Patienten der Psychiatrischen Poliklinik. Med Diss, Zürich (in preparation)

  • Nie NH, Hull CH, Jenkins JG, Steinbrenner K, Bent DH (1975) SPSS Statistical Package for the Social Sciences. McGraw-Hill, New York (2nd edition)

    Google Scholar 

  • Pearlin LI, Schooler C (1978) The Structure of Coping. J Hlth Soc Behav 19:2–21

    Google Scholar 

  • Pfortmüller J (1983) Validierung des Fragebogens SPIKE IV durch Korrelation mit Standard-Ratingskalen für Depression und Angst. Med Diss, Zürich

  • Rauchfleisch U (1979) Handbuch zum Rosenzweig Picture-Frustration Test (PFT) Bd 1+2. Huber, Bern

    Google Scholar 

  • Ruppen R, Müller U, Baumann U, Angst J (1973) Prüfung der Aussagegenauigkeit bei einer Befragung über Drogenkonsum. Z Präv Med 18:173–181

    Google Scholar 

  • Schepank H (1982) Epidemiologie psychogener Erkrankungen. Ein Beitrag zur Grundlagenforschung aus einer Feldstudie. Z Psychosom Med 28:104–125

    Google Scholar 

  • Schulsinger F, Mednick SA, Knop J (1981) Longitudinal ResearchMethods and Uses in Behavioral Science. Martinus Nijhoff Publ, Boston The Hague London

    Google Scholar 

  • Shepherd M, Cooper B, Brown AC, Kalton G (1981) Psychiatric Illness in General Practice. Oxford University Press, London (2nd ed)

    Google Scholar 

  • Srole L (1975) Measurement and Classification in Socio-Psychiatric Epidemiology: Midtown Manhattan Study (1954) and Midtown Manhattan Restudy (1974). J Hlth Soc Behav 4:347–365

    Google Scholar 

  • Srole L, Langner TS, Michael ST, Opler MK, Rennie TAC (1962) Mental Health in the Metropolis. McGraw Hill, New York

    Google Scholar 

  • Stassen HH (1983) Classification of schizo-affective patients by multidimensional scaling and cluster analysis. In: Angst J, Scharfetter C, Stassen HH (eds) Classification of schizo-affective patients by multidimensional scaling and cluster analysis. Psychiat Clin 16:254–264

    Google Scholar 

  • Sturt E, Bebbington P, Hurry J, Tennant C (1981) The Present State Examination used by interviewers from a Survey Agency: report from the MRC Camberwell Community Survey. Psychol Med 11:185–192

    Google Scholar 

  • Tennant C, Andrews G (1976) A Scale to Measure the Stress of Life Events. Aust NZJ Psychiatr 10:27–32

    Google Scholar 

  • Tennant C, Andrews G (1977) A Scale to Measure the Stress of Life Events. Aust NZJ Psychiatr 11:163–167

    Google Scholar 

  • Tur WA (1981) Validierung der Syndromliste SL an Diagnosen der militärischen Untersuchungskommission anIäßlich der Rekrutierung. Med Diss, Zürich

  • Uhlenhuth E, Haberman SJ (1977) Remembering life events. In: Strauss JS (ed) The Origins and Course of Psychopathology. Plenum, New York

    Google Scholar 

  • Weissman MM, Paykel ES (1974) The depressed woman, a study of social relationships. University of Chicago Press, Chicago

    Google Scholar 

  • Wing JK, Cooper JE, Sartorius N (1974) Measurement and Classification of Psychiatric Symptoms: An Instruction Manual for the PSE and Catego Program. Cambridge University Press, London

    Google Scholar 

  • Zerssen v D (1976) Klinische Selbstbeurteilungsskalen (KSb-S) aus dem Münchner Psychiatrischen Information s-System (PSYCHIS München). Paranoid-Depressivitäts-Skala Parallelformen PD-S und PD-S1. Manual. Beltz Test Gesellschaft mbH, Weinheim

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Project supported by grants 3.804.76 and 3.956.80 from the Swiss National Science Foundation

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Angst, J., Dobler-Mikola, A. & Binder, J. The Zurich study —A prospective epidemiological study of depressive, neurotic and psychosomatic syndromes. Eur Arch Psychiatr Neurol Sci 234, 13–20 (1984). https://doi.org/10.1007/BF00432878

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  • DOI: https://doi.org/10.1007/BF00432878

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