Summary
Arterial and coronary sinus blood levels of catecholamines, adenosine 3′, 5′-cyclic monophosphate (c-AMP) and lactate were measured during isometric exercise in fourteen patients. In no patient did lactate production occur. Mean resting total catecholamine levels both arterial (0.53±0.07 ng/ml; 2.94±0.38 nmol/l) and coronary sinus (0.4±0.08 ng/ml; 2.22±0.44 nmol/l), did not change significantly on exercise. Coronary sinus c-AMP levels fell on exercise from 11.5±0.8 nmol/l (resting) to 9.9±0.8 nmol/l (exercise) (P<0.01) with an arterial-coronary sinus difference of 1.2 nmol/l (P<0.01) on exercise.
Our findings suggest that isometric exercise does not normally result in excessive cardiac symphathetic activity.
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Robson, R.H., Fluck, D.C. Effect of isometric exercise on catecholamines in the coronary circulation. Europ. J. Appl. Physiol. 37, 289–295 (1977). https://doi.org/10.1007/BF00430958
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DOI: https://doi.org/10.1007/BF00430958