Summary
Peculiar periodically banded structures were found in the extracellular spaces of a vascular type of a murine osteosarcoma. The structures consisted of fine almost parallely arranged filaments with electron-dense cross-bands of about 35–50 nm thickness. The periodicity of the bands was about 85–100 nm. Similar structures have been found by many authors in various tissues of different species. Commonly, they have been referred to as “fibrous long-spacing collagen”.
Zusammenfassung
In einem vasculären Typ eines Osteosarkoms der Maus wurden eigenartige, im Bxtracellularraum gelegene, periodisch, gebänderte Strukturen festgestellt. Diese bestanden aus dünnen, nahezu parallel angeordneten Filamenten mit elektronendichten Querbändern von etwa 35–50 nm Breite. Die Periodizität der Bänderung betrug etwa 85–100 nm. Ähnliche Strukturen wurden von zahlreichen Autoren in verschiedenen Geweben mehrerer Species gefunden. Im allgemeinen werden sie als „fibrous long-spacing collagen” bezeichnet.
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Literatur
Banfield, W. G., Lee, C. K., Lee, C. W.: Myocardial collagen of the fibrous long-spacing type. Arch. Path. 95, 262–266 (1973)
Cervós-Navarro, J., Matakas, F., Lazaro, M. C.: Das Bauprinzip der Neurinome. Ein Beitrag zur Histogenese der Nerventumoren. Virchows Arch. Abt. A 345, 276–291 (1968)
Cravioto, H., Lockwood, R.: Long-spacing fibrous collagen in human acoustic nerve tumors. In vivo and in vitro observations. J. Ultrastruct. Res. 24, 70–85 (1968)
Gössner, W., Hindringer, B., Luz, A., Sehwabe, M.: Morphologie und Enzymhistochemie 224Ra-induzierter osteogener Sarkome bei der Maus. Z. Krebsforsch. 78, 225–235 (1972)
Gössner, W., Hug, O., Luz, A., Müller, W. A.: Experimental induction of bone tumors by short-lived bone-seeking radionuclides. In: Recent results in cancer research, Bd. 54, S. 36–49. Berlin-Heidelberg-New York: Springer 1976
Hashimoto, K., Ohyama, H.: Cross-banded filamentous aggregation in the human dermis. J. invest. Derm. 62, 106–112 (1974)
Kimura, K., Koizumi, F., Kihara, I., Kitamura, S.: Fibrous long spacing type collagen fibrils in the glomeruli of experimental amyloidosis in rabbit. Lab. Invest. 32, 279–285 (1975)
Luse, S.A., Zopf, D., Cox, J. W.: An electron microscopic study of in vitro and in vivo long-spacing collagen. Anat. Rec. 145, 254–255 (1963)
Marquart, K.-H.: Virus-like particles in 224Ra-induced murine osteosarcomas. Beitr. Path. 152, 116–126 (1974)
Marquart, K.-H., Luz, A., Gössner, W.: Zur Ultrastruktur des strahleninduzierten Osteosarkoms der Maus. Verh. dtsch. Ges. Path. 58, 434–437 (1974)
Mollo, F., Monga, G.: Banded structures in the connective tissue of lymphomas, lymphadenitis, and thymomas. Virchows Arch. Abt. B 7, 356–366 (1971)
Müller, W. A., Gössner, W., Hug, O., Luz, A.: Late effects after incorporation of the shortlived α-emitters 224Ra and 227Th in mice. Hlth Phys., im Druck (1976)
Pillai, P. A.: A banded structure in the connective tissue of nerve. J. Ultrastruct. Res. 11, 455–468 (1964)
Raimondi, A. J., Mullan, S., Evans, J. P.: Human brain tumors: an electron-microscopic study. J. Neurosurg. 19, 731–753 (1962)
Ramsey, H. J.: Fibrous long-spacing collagen in tumors of the nervous system. J. Neuropath. exp. Neurol. 24, 40–48 (1965)
Rohen, J. W.: Über das Ligamentum pectinatum der Primaten. Z. Zellforsch. 58, 403–421 (1962)
Schubert, G. E., Adam, A.: Glomerular nodules and long-spacing collagen in kidneys of patients with multiple myeloma. J. clin. Path. 27, 800–805 (1974)
Silberberg, R., Silberberg, M., Feir, D.: Occurrence of long-spacing (FLS) collagen in the articular cartilage of the mouse. Path, et Microbiol. (Basel) 26, 779–783 (1963)
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Durchgeführt im Rahmen eines EURATOM-Assoziationsvertrages (090-72-1 BIAD).
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Marquart, KH., Luz, A. & Gössner, W. Sogenanntes „Fibrous Long-Spacing Collagen” in einem Osteosarkom der Maus. Virchows Arch. A Path. Anat. and Histol. 370, 177–183 (1976). https://doi.org/10.1007/BF00430813
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DOI: https://doi.org/10.1007/BF00430813