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Freychet, P. Interactions of polypeptide hormones with cell membrane specific receptors: Studies with insulin and glucagon. Diabetologia 12, 83–100 (1976). https://doi.org/10.1007/BF00428972
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DOI: https://doi.org/10.1007/BF00428972
Key words
- Insulin
- glucagon
- polypeptide hormones
- receptors
- plasma membrane
- isolated liver cells
- isolated fat cells
- liver membranes
- fat cell membranes
- cardiac membranes
- adenylate cyclase
- monoiodoinsulin
- monoiodoglucagon
- 125I-insulin binding
- 125I-glucagon binding
- radioreceptorassay
- structure-function relationships
- modified insulins
- obese hyperglycémic (ob/ob) mouse
- obesity
- receptor defect
- insulin resistance
- insulin-dextran-ferritin
- visualization of binding sites