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Therapeutic effect of exercise on hypertension

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Summary

Arterial blood pressure, total peripheral resistance (TPR), plasma catecholamine and other hormone concentrations were measured or estimated during, and 4 h following, a 20-min exercise test on the bicycle ergometer in 10 women with marginal (borderline) hypertension. Each woman served as her own control by repeating the whole procedure, except for the exercise test, on another day. Median and 80% range was used: M (0.8 R). Compared with the control, the exercise reduced the driving blood pressure from 103 (94–110) to 95 (80–100) mm Hg and the TPR from 1.13 (0.96–1.40) to 0.91 (0.79–1.11) PRUS — both reductions being statistically significant with two-sided P<0.05 for at least 4 h. — The reduced nervous and humoral sympathetic activity following aerobic exercise seems capable of explaining the low TPR, and the continuous rise in the muscular vasodilatator dopamine may be of importance.

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Authors and Affiliations

  1. Institute of Medical Physiology B, University of Copenhagen, 30 Juliane Mariesvej, DK-2100, Copenhagen Ø

    Poul -Erik Paulev

  2. Department of Clinical Chemistry, University Hospital Gentofte, Denmark

    Robert Jordal & Ole Kristensen

  3. Medical Department P, Rigshospitalet, Copenhagen, Denmark

    JØrgen Ladefoged

Authors
  1. Poul -Erik Paulev
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  2. Robert Jordal
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  3. Ole Kristensen
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  4. JØrgen Ladefoged
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Supported by Hjerteforeningen and HÄssle, Denmark

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Paulev, P.E., Jordal, R., Kristensen, O. et al. Therapeutic effect of exercise on hypertension. Europ. J. Appl. Physiol. 53, 180–185 (1984). https://doi.org/10.1007/BF00422584

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  • DOI: https://doi.org/10.1007/BF00422584

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