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The action of chlorpromazine on exploration in pairs of rats

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Abstract

When two animals were placed in a hole-board the number of headdips made by each rat was twice the number made when tested alone, but was the same for pairs of drugged (2 mg/kg chlorpromazine) and undrugged rats, and for pairs where only one rat was drugged. This contrasts with the reduction of headdipping produced by chlorpromazine in single animals. However, chlorpromazine still reduced general motor activity, regardless of whether the partner was drugged or not. The activity of the undrugged rats was affected by the partner's state and was lower when the partner was drugged.

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File, S.E., Pope, J.H. The action of chlorpromazine on exploration in pairs of rats. Psychopharmacologia 37, 249–254 (1974). https://doi.org/10.1007/BF00421538

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  • DOI: https://doi.org/10.1007/BF00421538

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