Abstract
We report two cases of ventrolateral thoracic and lumbar meningoceles associated with neurofibromatosis type 1, and present a review of the literature. Thoracic and lumbar meningoceles are rare lesions which are associated with neurofibromatosis in 60% to 85% of cases. Large meningoceles may cause pain, neurological signs, or respirtory complaints when located intrathoracically. Surgery is indicated in such cases, as well as when small meningoceles enlarge with time. The etiology of meningoceles in neurofibromatosis remains controversial. The authors postulate that ventrolateral lesions of the thoracic and lumbar spine are secondary to congenital mesodermal dysplasia and hypoplastic bone changes. MRI is the diagnostic method of choice, since it most adequately visualizes the pathological anatomy of the spinal cord, meninges, and adjacent structures in every sectional plane. CT scans are pacticularly useful in assessing the spinal bony changes.
Similar content being viewed by others
References
Abe T, K Kojima, H Nishimura, M Uchida, M Doganemaru, H Ohtake: A case of intrathoracic meningocele accompanied by Recklinghausen's disease. Cardiac gated CINE MRI. Neuroradiology 32 (1990) 535
Angtuaco EJC, EF Binet, S Flanigan: Value of computed tomographic myelography in neurofibromatosis. Neurosurgey 13 (1983) 666–671
Bensaid AH, JL Dietemann, B Kastler, A GAngi, MY Jeung, A Wackenheim: Neurofibromatosis with dural ectasia and bilateral symmetrical pedicular clefts: report of two cases. Neuroradiology 34 (1992) 107–109
Booth AE: Lateral thoracic meningoceles. J Neurol Neurosurg Psichiat 32 (1969) 111–115
Bunner R: Lateral intrathoracic meningocele. Acta Radiol 51 (1959) 1–9
Byron FX, EE Alling, PC Samson: Intrathoracic meningocele. J Thorac Surg 18 (1949) 294–303
Chandler A, EE Herzberger: Lateral intrathoracic meningocele: case report with preoperative diagnosis. Am J Roentgenol 90 (1963) 1216–1219
Chee CP: Lateral thoracic meningocele associated with neurofibromatosis: total excision by posterolateral extradural approach. A case report. Spine 14 (1989) 129–131
Ciaglia P: Intrathoracic meningocele. J Thorac Surg 23 (1952) 183–292
Cross GO, JR Reavis, WW Saunders: Lateral intrathoracic meningocele. J Neurosurg 6 (1949) 423–432
Dolynchuk KN, J Teskey, M West: Intrathoracic meningocele associated with neurofibromatosis: case report. Neurosurgery 27 (1990) 485–487
Erkulvrawatr S, T ElGammai, J Hawkins, JB Green, G Strinivasan: Intrathoracic meningoceles and neurofibromatosis. Arch Neurol 36 (1979) 557–559
Freund B, C Timon: Cervical meningocele presenting as a neck mass in a patient with neurofibromatosis 1. J Laryngol Otol 106 (1992) 463–464
Geerts Y, M Marchau: Intrathoracic meningocele. J Spinal Disord 5 (1992) 116–121
Gibbens DT, N Argy: Chest case of the day: Lateral thoracic meningocele in a patient with neurofibromatosis. Am J Roentgenol 156 (1991) 1299–1300
Green WJ, AE Green Jr: Large pelvic mass in a patient with neurofibromatosis. Invest Radiol 23 (1988) 772–774
Ito Y, A Fukumura, E Urasaki Y Ushio: [A case of neurofibromatosis with spinal dural ectasia and vertebral body scalloping: a case report]. No Shinkei Geka 16 (1988) 1495–1499
Jamjoom ZAB, T Malabarey, TM Kolawole, K Araby: Lumbosacral dural anomalies in von Recklinghausen neurofibromatosis. Acta Neurochir 105 (1990) 140–146
Kaiser MC, RGM De Slegte, FC Crezee, J Valk: Anterior cervical meningoceles in neurofibromatosis. Am J Neuroradiol 7 (1986) 1105
Kawakami S, T Kimoto, M Noguchi, T Hashimoto, M Hase, Y Takashima, K Nishimura: [A case of lateral thoracic meningocele without neurofibromatosis]. Rinsho Hoshasen 35 (1990) 301–304
Kornberg M, GR Rechtine, TE Dupuy: Thoracic vertebral erosion secondary to an intrathoracic meningocele in a patient with neurofibromatosis. Spine 9 (1984) 821–824
La Veille CJ, DA Campbell: Neurofibromatosis and intrathoracic meningocele. Radiology 30 (1958) 62–66
Laws JW, C Pallis: Spinal deformities in neurofibromatosis. J Bone Joint Surg 45B (1963) 674–682
Leech RW, RA Olafson, RL Gilbertson, DR Shook: Intrathoracic meningocele and vertebral anomalies in a case of neurofibromatosis. Surg Neurol 9 (1978) 55–57
Maiuri F, G Corriero, F Giampaglia, L Simonetti: Lateral thoracic meningocele. Surg Neurol 26 (1986) 409–412
Mellion BT, Re George, DK Fischer, MD Lidsky, DS Baskin. Anterior sacral meningocele and tuberculous spondylitis of the sacrum in a patient with neurofibromatosis. Case report and review of the literature. Neurofibromatosis 2 (1989) 299–308
Miles J, J Pennybacker, P Sheldon: Intrathoracic meningocele: its development and association with neurofibromatosis. J Neurol Neurosurg Psachiat 32 (1969) 99–110
Nakasu Y, K Minouchi, N Hatsuda, S Nakasu, J Handa. Thoracic meningocele in neurofibromatosis: CT and MR findings. J Comput Assist Tomogr 15 (1991) 1062–1064
Nanson EM: Thoracic meningocele associated with neurofibromatosis. J Thorac Surg 33 (1957) 650–652
O'Nell PO, WJ Whatmore, AE Booth: Spinal meningoceles in association with neurofibromatosis. Neurosurgery 13 (1983) 82–84
Peeters FLM, B Verbeeten Jr: Expansion of the lumbosacral spinal canal in neurofibromatosis and ankylosing spondylitis. J Med Imaging 1 (1987) 236–240
Pohl R: Meningokele im Brustraum unter dem Bilde eines intrathorakalen Schattens. Roentgenpraxis 5 (1933) 747–749
Probst C: Multiple frontobasal meningoencephaloceles in neurofibromatosis. Neurofibromatosis 2 (1989) 233–237
Raison JCA: Intrathoracic meningoceles. Thorax 11 (1956) 334–340
Rapf C: Anterolaterale Meningozele. Röntgenblätter 39 (1986) 227–230
Robinson RG: Intrathoracic meningocele and neurofibromatosis. Br J Surg 51 (1964) 432–437
Sammons BP, DF Thomas: Extensive lumbar meningocele associated with neurofibromatosis. Am J Roentgenol 81 (1959) 1021–1025
Sarkar PK, AM Fagan. Intrathoracic meningocele in a patient with neurofibromatosis. Respir Med 85 (1991) 163–165
Scheltens P, CW Burger, J Valk, FW Bertelsmann. Anterolateral lumbar meningocele presenting as an ovarian cyst, in a patient with neurofibromatosis. Clin Neurol Neurosurg 91 (1989) 351–354
Sengpiel GW, FF Ruzicka, EA Lodmell: Lateral intrathoracic meningocele. Radiology 50 (1948) 515–520
Sepehr MH, P Vogel, M Kruger: Intrathorakale Meningozele bei der Neurofibromatose von Recklinghausen. Fortschr Geb Röntgenstr Nuklearmed 140 (1984) 102–104
Shealy CN, M Le May: Intrathoracic meningocele: two additional cases of this rare entity. J Neurosurg 21 (1964) 880–883
Shibuya M, M Mikoshiba, J Ikeda, Y Ito, T Miwa: A report of four cases of intrathoracic meningocele. No Shinkei Geka 20 (1992) 979–983
So CB, DK Li: Anterolateral cervical meningocele in association with neurofibromatosis: MR and CT studies. J Comput Assist Tomogr 13 (1989) 692–695
Weinreb JC, PH Arger, R Grossman, L Samuel: CT metrizamide myelography in multiple bilateral intrathoracic meningoceles. J Comput Asist Tomogr 8 (1984) 324–326
Yaghmai I: Spine changes in neurofibromatosis. Radiographics 6 (1986) 261–285
Yotsumoto K, H Morifuji, C Ohkubo, K Mitani; H Shimazu; M Nishi. [A successfully treated case of thoracic meningocele with von Recklinghausen's disease]. Nippon Kyobu Geka Gakkai Zasshi 40 (1992) 1249–1253
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rainov, N.G., Heidecke, V. & Burkert, W. Thoracic and lumbar meningocele in neurofibromatosis type 1. Report of two cases and review of the literature. Neurosurg. Rev. 18, 127–134 (1995). https://doi.org/10.1007/BF00417670
Issue Date:
DOI: https://doi.org/10.1007/BF00417670