Summary
Both chlorpromazine and homofenazine at 2 mg/kg, i.p. were found to inhibit the rats' passive avoidance response in a two-compartment apparatus when the animals were given five electric shocks in the small compartment before testing. The same effect was reduced when they were given 10 shocks. The results could not be explained by such factors as sensory deficit, locomotor inhibition, drug-learning dissociation and loss of attention due to the drug injection.
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Iwahara, S., Iwasaki, T. & Hasegawa, Y. Effects of chlorpromazine and homofenazine upon a passive avoidance response in rats. Psychopharmacologia 13, 320–331 (1968). https://doi.org/10.1007/BF00414343
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DOI: https://doi.org/10.1007/BF00414343