Summary
The clinical experimental model of HLI application in the therapy of skin and mucosal cancers of the head and neck has opened new prospects in HLI utilization. Based on clinical observations and research in may be concluded that HLI, if applied topically in the area of the tumor, may induced its disappearance or regression. If applied presurgically, it blocks the dispersion of neocytes during surgery. Also, HLI inhibits metastatic dissemination of malignant tumors and therefore might reduce the percentage of patients with recurrence, decreasing the chance of survival of any other primary tumor.
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Padovan, I., Brodarec, I., Ikić, D. et al. Effect of interferon in therapy of skin and head and neck tumors. J Cancer Res Clin Oncol 100, 295–310 (1981). https://doi.org/10.1007/BF00410690
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DOI: https://doi.org/10.1007/BF00410690