Summary
5-Bromodeoxyuridine (BrdUrd) injected into the muscular tissue of fish bearing melanoma or neuroblastoma induces the production of virus-like particles in these tumors. The particles in the melanoma are morphologically similar to papovaviruses of polyoma-type, those in the neuroblastoma resemble oncornavirouses of B- and C-type.
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Supported by the Deutsche Forschungsgemeinschaft through Sonderforschungsbereich 103 “Zellenergetik und Zelldifferenzierung”, Marburg, and by Justus-Liebig-Universität Gießen
This paper contains parts of the doctoral dissertation of G. Kollinger
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Kollinger, G., Schwab, M. & Anders, F. Virus-like particles induced by bromodeoxyuridine in melanoma and neuroblastoma of xiphophorus. J Cancer Res Clin Oncol 95, 239–246 (1979). https://doi.org/10.1007/BF00410645
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DOI: https://doi.org/10.1007/BF00410645