Summary
The scanning electron microscope was used to compare the appearances of the endothelial monolayer of the trabecular wall of Schlemm's canal in the rhesus monkey after exposure to intracameral pressures of 8, 15 and 22 mm Hg for one hour.
Over this pressure range, the bulges in the spindle-shaped structures in the monolayer became rounder in shape and the number of openings on the surface was apparently greater at 22 mm Hg than at 15 and 8 mm Hg. A quantitative comparison between the tissue at 8 and 15 mm Hg showed a statistically significant increase in the number of openings on the bulges at 15 mm Hg.
Zusammenfassung
Mit Hilfe des Rasterelektronenmikroskopes wurde an Rhesusaffen das Verhalten des Endothels der trabekulären Seite des Schlemmschen Kanals bei Vorderkammerdrucken von 8, 15 und 22 mm Hg untersucht. Die Expositionszeit für diese Drucke betrug jeweils 1 Std. Proportional zur Höhe des Druckes wurden die Vorwölbungen der spindelförmigen Strukturen im Endothel runder. Die Zahl der Öffnungen in der Oberfläche war bei 22 mm eindeutig größer als bei 15 und 8 mm Hg. Ein quantitativer Vergleich des Gewebes bei 8 und 15 mm Hg zeigte bei 15 mm Hg eine statistisch signifikante Vermehrung der Zahl der Öffnungen.
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Lee, W.R., Grierson, I. Pressure effects on the endothelium of the trabecular wall of Schlemm's canal: A study by scanning electron microscopy. Albrecht von Graefes Arch. Klin. Ophthalmol. 196, 255–265 (1975). https://doi.org/10.1007/BF00410037
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DOI: https://doi.org/10.1007/BF00410037