Summary
The effect of amphetamine on the daily meal frequency and the average meal size of 11 albino rats was investigated. During a 7 day period the animals were given a solution of amphetamine sulphate (0.023 g/100 ml) instead of water. The animals showed a significant (p<0.01) decrease of the daily food intake. The frequency of intake of food (“meals”) was mainly unchanged, while the average meal size and the ratio of daily average meal size and meal frequency were decreased. This is interpreted as caused by a selective stimulating effect of amphetamine on the satiety system. The feeding system which also forms a part of food homeostasis is not discernably influenced by amphetamine.
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Borbély, A., Waser, P.G. Das Freßverhalten der Ratte. Psychopharmacologia 9, 373–381 (1966). https://doi.org/10.1007/BF00406448
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DOI: https://doi.org/10.1007/BF00406448