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The lack of effect of 11 α-hydroxyprogesterone on the flank-organ and ear sebaceous glands of adult male Syrian golden hamsters

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References

  1. Voigt W, Fernandez EP, Hsia SL (1970) Transformation of testosterone into 17B-hydroxy-5α-androstan-3-one by microsomal preparations of human skin. J Biol Chem 245:5594–5599

    PubMed  Google Scholar 

  2. Mauvais-Jarvis P, Kuttenn F, Baudot N (1974) Inhibition of testosterone conversion to dihydrotestosterone in men treated percutaneously by progesterone. J Clin Endocrinol Metab 38:142–147

    PubMed  Google Scholar 

  3. Girard J, Barbier A, lafille C (1980) Inhibition of testosterone metabolism and lipogenesis in animal sebaceous glands by progesterone. Arch Dermatol Res 269:281–290

    PubMed  Google Scholar 

  4. Byrnes WW, Stafford RO, Olson KJ (1953) Anti-gonadal hormone activity of 11α-hydroxyprogesterone. Proc Soc Exp Biol Med 82:243–247

    PubMed  Google Scholar 

  5. Tamm J, Seckelmann M, Volkwein U, Ludwig E (1982) The effect of the antiandrogen 11α-hydroxyprogesterone on sebum production and cholesterol concentration of sebum. J Dermatol 107:63–70

    Google Scholar 

  6. Frost P, Gomez EC (1972) Inhibitors of sex hormones: development of experimental models. In: Montagna W, Staughton RB, Van Scott EJ (eds) Advances in biology of skin, vol 12. Pharmacology and the skin. Appleton-Century-Crofts, New York, pp 403–420

    Google Scholar 

  7. Goos CMAA, Wirtz P, Vermorken AJM (1982) An improved method for the evaluation of antiandrogens. Arch Dermatol Res 273:333–341

    PubMed  Google Scholar 

  8. Plewig G, Luderschmidt C (1977) Hamster ear model for sebaceous gland. J Invest Dermatol 68:171–176

    Article  PubMed  Google Scholar 

  9. Luderschmidt C, Eiermann W, Jawny J (1983) Steroid hormone receptors and their relevance for sebum production in the sebaceous gland ear model of the Syrian hamster. Arch Dermatol Res 275:175–180

    PubMed  Google Scholar 

  10. Matias JR, Orentreich N (1983) The hamster ear sebaceousglands. I. Examination of the regional variation by stripped skin planimetry. J Invest Dermatol 81:43–46

    Article  PubMed  Google Scholar 

  11. Matias JR, Orentreich N, Malloy V (1983) The effect of the intracutaneous injection of progesterone on the flank organ of intact, sexually mature male Syrian hamster. J Invest Dermatol 80:358

    Article  Google Scholar 

  12. Malloy V, Matias JR, Orentreich N (1983) The inhibitory effect of topical progesterone on the flank organ of intact sexually mature male Syrian golden hamsters. Clin Res 31:585

    Google Scholar 

  13. Simpson NB, Cunliffe WJ, Hodgins MB (1983) The relationship between the in vitro activity of 3B-hydroxysteroid dehydrogenase Δ4 − 5 isomerase in human sebaceous glands and their secretory activity in vivo. J Invest Dermatol 81:139–144

    Article  PubMed  Google Scholar 

  14. Simpson NB and Martin AR (1983) A more reliable photometric technique for the measurement of scalp sebum excretion. Br J Dermatol 109:647–652

    PubMed  Google Scholar 

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Matias, J.R., Orentreich, N., Malloy, V. et al. The lack of effect of 11 α-hydroxyprogesterone on the flank-organ and ear sebaceous glands of adult male Syrian golden hamsters. Arch Dermatol Res 276, 346–348 (1984). https://doi.org/10.1007/BF00404633

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  • DOI: https://doi.org/10.1007/BF00404633

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