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Study on the excitation induced by amphetamine, cocaine and α-methyltryptamine

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Summary

Atropine and benactyzine enhance the hypermotility produced by amphetamine and cocaine, but diminish the hypermotility caused by α-methyltryptamine. Tremorine decreases amphetamine hypermotility. Methylsergide increases hypermotility produced by amphetamine and does not influence the effect of cocaine and α-methyltryptamine. Chlorpromazine and phenoxybenzamine diminish hypermotility produced by all the three excitants.

Reserpine inhibits the effect of cocaine and α-methyltryptamine and does not influence that of amphetamine.

Prenylamine diminishes the effect of amphetamine, cocaine and methyltryptamine.

The possible significance of these findings is discussed.

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Authors and Affiliations

  1. Department of Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Hungary

    Éva Galambos, A. Klára Pfeifer, L. György & J. Molnár

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  1. Éva Galambos
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  2. A. Klára Pfeifer
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  3. L. György
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  4. J. Molnár
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Galambos, É., Pfeifer, A.K., György, L. et al. Study on the excitation induced by amphetamine, cocaine and α-methyltryptamine. Psychopharmacologia 11, 122–129 (1967). https://doi.org/10.1007/BF00401248

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  • DOI: https://doi.org/10.1007/BF00401248

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