Abstract
The authors describe the case of a 53-year-old woman who suffered from an Aspergillus fumigatus infection of the L2/3 intervertebral disc space unrelated to previous operations on her lumbar spine. After surgical debridement combined with amphotericin therapy she died on the 23rd postoperative day from a fulminant bacterial sepsis of pulmonary origin. Although she had intermittently used steroids for bronchial asthma, this is an unusual case of fungal infection of the lumbar spine in an apparently immunocompetent patient.
References
Assaad W, Nuchikat PS, Cohen L, Esguerra JV, Whittier FC (1994) Aspergillus discitis with acute disc abscess. Spine 19: 2226–2229
Barnwell PA, Jelsma LF, Raff MJ (1985) Aspergillus osteomyelitis. Report of a case and review of the literature. Diagn Microbiol Infect Dis 3: 515–519
Bongartz EB, Ulrich P, Fidler M, Bernucci C (1994) Reoperation in the management of post-operative disc space infection. Zentralbl Neurochir 55: 120–124
Casey AT, Wilkins P, Uttley D (1994) Aspergillosis infection in neurosurgical practice. Br J Neurosurg 8: 31–39
Castelli C, Benazzo F, Minoli L, Marone P, Seghezzi R, Carlizzi CN (1990) Aspergillus infection of the L3-L4 disc space in an immunosuppressed heart transplant patient. Spine 15: 1369–1373
Cortet B, Deprez X, Triki R, Savage C, Flipo RM, Duquesnoy B, Delcambre B (1993) Les spondylodiscites aspergillaires. A propos de cinq observations. Rev Rhum Ed Fr 60: 37–44
Cortet B, Richard R, Deprez X, Lucet L, Flipo RM, Le Loet X, Duquesnoy B, Delcambre B (1994) Aspergillus spondylodiscitis: successful conservative treatment in 9 cases. J Rheumatol 21: 1287–1291
D'Hoore K, Hoogmartens M (1993) Vertebral aspergillosis. A case report and review of the literature. Acta Orthop Belg 59: 306–314
Govender S, Rajoo R, Goga IE, Charles RW (1991) Aspergillus osteomyelitis of the spine. Spine 16: 746–749
Holmes PF, Osterman DW, Tullos HS (1988) Aspergillus discitis. Report of two cases and review of the literature. Clin Orthop 240–246
Hummel M, Schuler S, Weber U, Schwertlick G, Hempel S, Theiss D, Rees W, Mueller J, Hetzer R (1993) Aspergillosis with Aspergillus osteomyelitis and diskitis after heart transplantation: surgical and medical management. J Heart Lung Transplant 12: 599–603
Mawk JR, Erickson DL, Chou SN, Seljeskog EL (1983) Aspergillus infections of the lumbar disc spaces. Report of three cases. J Neurosurg 58: 270–274
McGregor A, McNicol D, Collignon P (1992) Aspergillus-induced discitis. A role for itraconazole in therapy? Spine 17: 1512–1514
Morgenlander JC, Rossitch E Jr, Rawlings CE (1989) Aspergillus disc space infection: case report and review of the literature. Neurosurgery 25: 126–129
Peters-Christodoulou MN, de Beer FC, Bots GT, Ottenhoff TM, Thompson J, van't Wout JW (1991) Treatment of postoperative Aspergillus fumigatus spondylodiscitis with itraconazole. Scand J Infect Dis 23: 373–376
Post MJ, Sze G, Quencer RM, Eismont FJ, Green BA, Gahbauer H (1990) Gadolinium-enhanced MR in spinal infection. J Comput Assist Tomogr 14: 721–729
Schulitz KP, Assheuer J (1994) Discitis after procedures on the intervertebral disc. Spine 19: 1172–1177
Scully RE, Mark EJ, McNeely WF, McNeely BU (1991) Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 11-1991. A 65-year-old man with a vertebral and disk lesion after a pulmonary operation for Aspergillus infection. N Engl J Med 324: 754–763
Tack KJ, Rhame FS, Brown B, Thompson RC Jr (1982) Aspergillus osteomyelitis. Report of four cases and review of the literature. Am J Med 73: 295–300
Thibodeau AA (1968) Closed space infection following removal of lumbar intervertebral disc. J Bone Joint Surg [Am] 50: 400–410
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Lang, E.W., Pitts, L.H. Intervertebral disc space infection caused by Aspergillus fumigatus . Eur Spine J 5, 207–209 (1996). https://doi.org/10.1007/BF00395517
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DOI: https://doi.org/10.1007/BF00395517