Summary
Volume averaging, relatively slight differences in the mean attenuation coefficients of CSF and white/grey matter, and the irregular contours of the human ventricular system have so far seriously limited the accuracy of CT estimation of ventricular volume. Taking advantage of the high attenuation of metrizamide-containing CSF, we have developed three methods for computing ventricular volume after metrizamide CT ventriculography; these methods depend upon computer analysis of X-ray absorption data obtained from contiguous CT brain slices. All three methods were validated by CT scanning a formalin-fixed cadaver brain containing an epoxy-resin cast of the ventricular system. Calculated ventricular volumes were compared with the actual measured volume of the ventricular cast.
Similar content being viewed by others
References
Last, R.J., Tompsett, D.H.: Casts of the cerebral ventricles. Br.J.Surg. 40, 525–543 (1953)
Penn, R.D., Belanger, M.G., Yasnoff, W.A.: Ventricular volume in man computed from CAT scans. Ann.Neurol. 3, 216–223 (1978)
Pentlow, K.S., Rottenberg, D.A., Deck, M.D.F.: Partial volume summation: a simple approach to ventricular volume determination from computed tomography. (These proceedings, pp. 130–132)
Rottenberg, D.A., Deck, M.D.F., Allen, J.C.: Metrizamide washout as a measure of CSF bulk flow. (These proceedings, pp. 203–206)
Rottenberg, D.A., Howieson, J., Deck, M.D.F.: The rate of CSF formation in man: preliminary observations on metrizamide washout as a measure of CSF bulk flow. Ann.Neurol. 2, 503–510 (1977)
Walser, R.L., Ackerman, L.V.: Determination of volume from computerized tomograms: finding the volume of fluid-filled brain cavities. J.Comp.Assist.Tomogr. 1, 117–130 (1977)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rottenberg, D.A., Pentlow, K.S., Deck, M.D.F. et al. Determination of ventricular volume following metrizamide CT ventriculography. Neuroradiology 16, 136–139 (1978). https://doi.org/10.1007/BF00395228
Issue Date:
DOI: https://doi.org/10.1007/BF00395228