Summary
The cross b2-17-A4 x b2+ involving 2 mutant sites located one at each end of the b2 locus in Ascobolus immersus was analysed in order to look for aberrant segregations at one site among asci with aberrant 4:4 segregation at the other site. Most double site conversion asci with an aberrant 4:4 at one site showed a 5:3 segregation at the other site. Almost always, the aberrant 4:4 involved the low conversion end site and the 5:3 involved the high conversion end site. It is concluded that, in each individual meiosis, symmetrical hybrid DNA is often, if not always, physically associated with asymmetrical hybrid DNA. The asymmetrical hybrid DNA portion lies near the high conversion end and the symmetrical hybrid DNA portion near the low one.
Similar content being viewed by others
References
Catcheside, D. G.: In: The genetics of recombination (K. R. Lewis and B. John, eds.), 172 pp. London: Arnold 1977
Hastings, P. J.: An. Rev. Genet. 9, 129–144 (1975)
Holliday, R.: Genet. Res. 5, 282–304 (1964)
Leblon, G.: Mol. Gen. Genet. 115, 36–48 (1972)
Leblon, G.: Genetics 92, 1093–1106 (1979)
Leblon, G., Rossignol, J. L.: Mol. Gen. Genet. 122, 265–282 (1973)
Leblon, G., Rossignol, J. L.: Heredity 42, 337–352 (1979)
Lissouba, P., Mousseau, J., Rizet, G., Rossignol, J.-L.: Adv. Genet. 11, 343–380 (1962)
Meselson, M., Radding, C. M.: Proc. Nat. Acad. Sci. USA 72, 358–361 (1975)
Nicolas, A.: Carte génétique et fréquences de conversion dans le génome d'Ascobolus immersus. Thèse Doctorat 3ème cycle, 108 pp. Université Paris-Sud, Centre d'Orsay (1978)
Paquette, N.: Can. J. Genet. Cytol. 20, 9–17 (1978)
Paquette, N., Rossignol, J. L.: Mol. Gen. Genet. 163, 313–326 (1978)
Rizet, G., Engelmann, C., Lefort, C., Lissouba, P., Mousseau, J.: C. R. Acad. Sci. (D) (Paris) 250, 2050–2052 (1960)
Rizet, G., Rossignol, J. L., Lefort, C.: C. R. Acad. Sci. (D) (Paris) 269, 1427–1430 (1969)
Rossignol, J. L., Haedens, V.: Heredity 40, 405–425 (1978)
Rossignol, J. L., Paquette, N.: Proc. Nat. Acad. Sci. USA 76, 2871–2875 (1979)
Sobell, H. M.: Proc. Nat. Acad. Sci. USA 69, 2483–2487 (1972)
Stadler, D. R.: An. Rev. Genet. 7, 113–127 (1973)
Wagner, R. E., Radman, M.: Proc. Nat. Acad. Sci. USA 72, 3619–3622 (1975)
Whitehouse, H. L. K.: Nature (London) 199, 1034–1040 (1963)
Yu-Sun, C. C. C.: Am. J. Bot. 51, 231–237 (1964)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rossignol, J.L., Haedens, V. Relationship between asymmetrical and symmetrical hybrid DNA formation during meiotic recombination. Curr Genet 1, 185–191 (1980). https://doi.org/10.1007/BF00390942
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00390942