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Pathogenesis, clinic, and treatment of ganglion

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Summary

In clarification of various theories on the pathogenesis of the ganglion, histopathologic examinations indicate that the ganglion develops from connective tissue by myxoid degeneration and disintegration of collagen fibers. Increasing amounts of mucinous fluid accumulate by the progressive liquefaction of collagen fibers and are surrounded by densifying collagen bundles which form a delimiting capsule. In view of the inadequacy of conservative treatment and the shortcomings of excision, the subcutaneous (s.c.) discission of the ganglion with a tenotome is recommended. Of 184 patients treated in this way, 151 displayed full healing, six underwent a successful repetition of the procedure, nine underwent an excision of the recurrent ganglion, and 18 rejected further treatment.

Zusammenfassung

Zur Klärung der verschiedenen Theorien fiber die Pathogense der Ganglien erwiesen histopathologische Untersuchungen, daß das Ganglion aus Bindegewebe durch Zerfall and myxoide Degeneration von Kollagenfasern mit Ansammlung schleimiger Flüssigkeit and Verdichtung der umgebenden Kollagenbündel entsteht. Als Behandlung wird die subcutane (s.c.) Diszission des Ganglion empfohlen. Von 184 derartig behandelten Patienten boten 151 vollständige Heilung dar, sechs unterzogen sich einer erfolgreichen Wiederholung des Verfahrens, neun machten eine sekundäre Exzision mit und 18 lehnten eine weitere Behandlung ab.

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Soren, A. Pathogenesis, clinic, and treatment of ganglion. Arch. Orth. Traum. Surg. 99, 247–252 (1982). https://doi.org/10.1007/BF00381402

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