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Study of the neurobehavioural toxicity of styrene at low levels of exposure

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Summary

Thirty workers in a dockyard exposed to concentrations of styrene lower than the TLV-TWA of 50 ppm and 30 control workers not subject to exposure but employed by the same company were subjected to three psychometric tests on one Monday morning and evening. The results were usually better in the evening than in the morning in both groups, which proves the lack of acute intoxication at the end of the day at this level of exposure. On the other hand, all of the tests conducted on the exposed subjects are significantly less good than those on the controls. The results suggest the existence of minor but significant organic mental disorders in the subjects exposed to a mean dose of 30 Wpm in this study. These results are inconsistent with those of several recent studies. The advisability of lowering the TLV of 50 Wpm in discussed.

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References

  • Cherry N, Waldrom HA, Wells G, Wilkinson R, Wilson H, Jones S (1980) An investigation of the acute behavioural effects of styrene on factory workers. Br J Ind Med 37:234–240

    PubMed  Google Scholar 

  • Edling C, Ekberg K (1985) No acute behavioural effects of exposure to styrene: a safe level of exposure? Br J Ind Med 42:301–304

    PubMed  Google Scholar 

  • Flodin U, Ekberg K, Andersson L (1989) Neuropsychiatric effects of low exposure to styrene. Br J Ind Med 46:805–808

    PubMed  Google Scholar 

  • Gottel P, Axelson O, Lindelof B (1972) Field studies on human styrene exposure. Work Environ Health 9:76–83

    Google Scholar 

  • Harkonen H (1977) Relationship of symptoms to occupational styrene exposure and to the finding of electroencephalographic and psychological examination. Int Arch Occup Environ Health 40:231–239

    PubMed  Google Scholar 

  • Harkonen H, Lindström K, Seppalainen AM (1978) Exposure-response relationship between styrene exposure and central nervous functions. Scand J Work Environ Health 4:53–59

    Google Scholar 

  • Ikeda M, Koizumi A, Miyashka, Watanabe T (1982) Styrene exposure and biologic monitoring in F.R.P. boat production plants. Int Arch Occup Environ Health 49:325–339

    PubMed  Google Scholar 

  • Lindström K, Harkonen H, Hernberg S (1978) Disturbances in psychological functions of workers occupationally exposed to styrene. Scand J Work Environ Health 4:129–139

    Google Scholar 

  • Mackay CJ, Kelman GR (1986) Choice reaction time in workers exposed to styrene vapour. Hum Toxcicol 5:85–89

    Google Scholar 

  • Mutti A, Mazzucchi A, Rusticelli P, Frigeri G, Arfini G, Franchini I (1984) Exposure-effect and exposure-response relationships between occupational exposure to styrene and neurophysiological functions. Am J Ind Med 5:275

    PubMed  Google Scholar 

  • Triebig G, Lehrl S, Weltle D, Schaller KM, Valentin H (1989) Clinical and neurobehavioural study of the acute and chronic neurotoxicity of styrene. Br J Ind Med 46:799–804

    PubMed  Google Scholar 

  • Van Der Linden M (1989) Les troubles de la mémoire. Bruxelles (Pierre Mardaga)

    Google Scholar 

Download references

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Jégaden, D., Amann, D., Simon, J.F. et al. Study of the neurobehavioural toxicity of styrene at low levels of exposure. Int. Arch Occup Environ Heath 64, 527–531 (1993). https://doi.org/10.1007/BF00381103

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  • DOI: https://doi.org/10.1007/BF00381103

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