Summary
Analysis of 426 alleles of the human Ha-ras 1 locus in DNA samples of cancer patients and controls reveals no obvious association between specific restriction fragments and a genetic predisposition to malignancy. However, differences in the allele distribution in leukocyte and tumour DNAs of cancer patients may be related to an involvement of the Ha-ras1 gene in tumorigenesis.
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Corell, B., Zoll, B. Comparison between the allelic frequency distribution of the Ha-ras 1 locus in normal individuals and patients with lymphoma, breast, and ovarian cancer. Hum Genet 79, 255–259 (1988). https://doi.org/10.1007/BF00366247
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DOI: https://doi.org/10.1007/BF00366247