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Structural heterogeneity of human Pgp-1 and its relationship with p85

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References

  • Cleveland, D. W., Stuart, G. F., Kirschner, M. W., and Laemmli, U. K.: Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J. Biol, Chem. 252: 1102–1106, 1977

    Google Scholar 

  • Colombatti, A., Hughes, F. N. Taylor, B. A., and August, J. T.: Gene for a major cell surface glycoprotein of mouse macrophages and other phagocytic cells is on chromosome 2. Proc. Natl. Acad. Sci. U.S.A. 79: 1926–1929, 1982

    Google Scholar 

  • Cruz, T. F., Quackenbush, E. J., Letarte, M., and Moscarello, M. A.: Elevated levels of a glycoprotein antigen in gray and white matter of brain from victims of multiple sclerosis. Neurochem. Res. 11: 877–889, 1986

    Google Scholar 

  • Dalchau, R., Kirkley, J., and Fabre, J. W.: Monoclonal antibody to a human brain-granulocyte-T lymphocyte antigen probably homologous to the W 3/13 antigen of the rat. Eur. J. Immunol. 10: 745–749, 1980

    Google Scholar 

  • Fabricant, R. N., DeLarco, J. E., and Todaro, G. J.: Nerve growth factor receptors in human melanoma cells in culture. Proc. Natl. Acad. Sci. U.S.A. 74: 565–569, 1977

    Google Scholar 

  • Fogh, J., Wright, W. C., and Loveless, J. D.: Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J. Natl. Cancer Inst. 58: 209–214, 1977

    Google Scholar 

  • Gootenberg, J. E., Ruscetti, F. W., Mier, J. W., Gazdar, A. and Gallo, R. C.: Human cutaneous T cell lymphoma and leukemla cell lines produce and respond to T cell growth factor. J. Exp. Med. 154: 1403–1418, 1981

    Google Scholar 

  • Haynes, B. F., Harden, E. A., Telen, M. J., Hemler, M. E., Strominger, J. L., Palker, T. J., Scearce, R. M., and Eisenbarth, G. S.: Differentiation of human T lymphocytes. I. Acquisition of a novel human cell surface protein (p80) during normal intrathymic T cell maturation. J. Immunol. 131: 1195–1200, 1983

    Google Scholar 

  • Hughes, E. N. and August, J. T.: Characterization of plasma membrane proteins identified by monoclonal antibodies. J. Mol. Chem. 256: 664–671, 1981

    Google Scholar 

  • Hughes, E. N., Colombatti, A., and August, J. T.: Murine cell surface glycoproteins. Purification of the polymorphic Pgp-1 antigen and analysis of its expression on macrophages and other myeloid cells. J. Biol. Chem. 258: 1014–1021, 1983

    Google Scholar 

  • Hyman, R., Lesley, J., Schulte, R., and Trotter, J.: Progenitor cells in the thymus: most thymus-homing progenitor cells in the adult mouse thymus bear Pgp-1 glycoprotein but not interleukin-2 receptor on their cell surface. Cell. Immunol. 101: 320–327, 1986

    Google Scholar 

  • Isacke, C. M., Sauvage, C. A., Hyman, R., Lesley, J., Schulte, R., and Trowbridge, I. S.: Identification and characterization of the human Pgp-1 glycoprotein. Immunogenetics 23: 326–332, 1986

    Google Scholar 

  • Jalkanen, S., Bargatze, R. F., de los Toyos, J., and Butcher, E. C.: Lymphocyte recognition of high endothelium: antibodies to distinct epitopes of an 85-95 kD glycoprotein antigen differentially inhibit lymphocyte binding to lymph node, mucosal, or endothelial cells. J. Cell Biol. 105: 983–990, 1987

    Google Scholar 

  • Laemmli, U. R.: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680–685, 1970

    Google Scholar 

  • Laskey, R. A. and Mills, A. D.): Enhanced autoradiographic detection of 32P and 125I using intensifying screens and bypersensitized film. FEES Lett, 82: 314–316, 1977

    Google Scholar 

  • Lesley, J., Hyman, R., and Schulte, R.: Evidence that the Pgp-1 glycoprotein is expressed on thymus homing progenitor cells of the thymus. Cell. Immunol. 91: 397–403, 1985a

    Google Scholar 

  • Lesley, J., Trotter, J., and Hyman, R.: The Pgp-1 antigen is expressed on early fetal thymocytes. Immunogenetics 22: 149–157, 1985b

    Google Scholar 

  • Letarte, M.: Human p83 glycoprotein bears three distinct epitopes defined by several monoclonal antibodies. Mol. lmmunol. 23: 639–644, 1986

    Google Scholar 

  • Letarte, M., Hurbe, S., and Quackenbush, E. J.: A glycoprotein of molecular weight 85,000 on human cells of B-lineage: detection with a firmly of monoclonal antibodies. Mol. Immunol. 22: 113–124, 1985

    Google Scholar 

  • McKenzie, J. L., Dalchau, R. and Fabre, J. W.: Biochemical charac-terization and localization in brain of a human brain-leucocyte meml-brane glycoprotein recognised by a monoclonal antibody. J. Neurochem. 39: 1461–1466, 1982

    Google Scholar 

  • Moore, A. E., Sabachewsky, L., and Toolan, H. W.: Culture characteristics of four permanent lines of human cancer cells. Cancer Res. 15: 598–602, 1955

    Google Scholar 

  • Omary, M. B. and Trowbridge, I. S.: Covalent binding of fatty acid to the transferrin receptor in cultured human cells. J. Biol. Chem. 256: 4715–4718, 1981

    Google Scholar 

  • Quackenbush, E. J., Cruz, T. F., Moscarello, M. A., and Letarte, M.: Identification of three antigens in human brain associated with similar antigens on human leukaemic cells. Biochem. J. 225: 291–299, 1985

    Google Scholar 

  • Quackenbush, E. J., Gougos, A., Baumal, R., and Letarte, M.: Differential localization within human kidney of five membrane proteins expressed on acute lymphoblastic leukemia cells. J. Immunol. 136: 118–124, 1986

    Google Scholar 

  • Telen, M. J., Eisenbarth, G. S., and Haynes, B. F.: Human erythrocyte antigens. Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran In(Lu) gene. J. Clin. Invest. 71: 1878–1886, 1983

    Google Scholar 

  • Trowbridge, I. S., Lesley, J., Schulte, R., Hyman, R., and Trotter, J.: Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues. Immunogenetics 15: 299–312, 1982

    Google Scholar 

  • Trowbridge, I. S., Lesley, J., Trotter, J., and Hyman, R.: Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor β-chain gene. Nature 315: 666–669, 1985

    Google Scholar 

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Omary, M.B., Trowbridge, I.S., Letarte, M. et al. Structural heterogeneity of human Pgp-1 and its relationship with p85. Immunogenetics 27, 460–464 (1988). https://doi.org/10.1007/BF00364434

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  • DOI: https://doi.org/10.1007/BF00364434

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