Skip to main content
SpringerLink
Log in

Zum nervösen Mechanismus der funktionellen Dilatation der Piaarterien

  • Published:
Pflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere Aims and scope Submit manuscript

Zusammenfassung

Eine mikrochirurgische Technik wurde entwickelt, die es gestattete, die Nervenbahnen zu unterbrechen, welche die weiche Hirnhaut durchdringend die Hirnrinde mit den Piaarterien direkt verbinden. Bei Kaninchen verursachte diese Operation ein Verschwinden der funktionellen Vasodilatation der Piaarterien, welche gewöhnlich unter den Bedingungen einer erhöhten Rindenaktivität (nach lokaler Strychninapplikation) oder nach 1–2 min langer Unterbrechung des Blutkreislaufes im Hirn auftreten. Die Reaktionen der operierten Arterien bei Erhöhung des pCO2 im Blut oder bei Änderungen des intravasculären Druckes waren beibehalten, wenn auch vermindert. Die Größe der Reaktion der Piaarterien bei Acetylcholineinwirkung (welche offensichtlich durch die Größe des Stoffwechselbedarfes der Hirnrinde bedingt ist) hängt auch ab von den Nervenimpulsen in den Nervenfasern, welche die Hirnrinde mit den Piaarterien unmittelbar verbinden.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Fog, M.: Cerebral circulation. II Reaction of pial arteries to increase in blood pressure. Arch. Neurol. Psychiat. (Chic.) 41, 260–268 (1939).

    Google Scholar 

  2. Forbes, H. S., G. I. Nason, and R. C. Wortman: Cerebral circulation. XLIV. Vasodilatation in the pia following stimulation of the vagus, aortic and carotid sinus nerves. Arch. Neurol. Psychiat. (Chic.) 37, 334–350 (1937).

    Google Scholar 

  3. Ingvar, D. H.: Cortical state of excitability and cortical circulation. In: Reticular formation of the brain, pp. 381–408, Boston: Little, Brown & Comp. 1958.

    Google Scholar 

  4. Kety, S. S.: The cerebral circulation. Chapt. LXXI in Handbook of Physiology, Sect. 1, Neurophysiology, vol. 3, pp. 1751–1760. Washington: Am. Physiol. Soc. 1960.

    Google Scholar 

  5. Klosowski, B. N.: Circulation of blood in the brain (in Russian), Moscow: Medgiz 1951.

    Google Scholar 

  6. Mchedlishvili, G. I.: On the independent nature of mechanisms regulating lumen of regional arteries of the brain (internal carotid and vertebral) and pial arteries (in Russian with English summary). Bull. biol. Med. exp. USSR. 49, No. 6, 21–25 (1960).

    Google Scholar 

  7. — Changes in the circulation during restoration of vital activity, owing to provoked intraarterial blood pumping (in Russian with English summary). Path. Physiol. exp. Therap. (USSR) 4, No. 4, 14–20 (1960).

    Google Scholar 

  8. —, and L. G. Ormotsadze: Haemodynamic mechanisms underlying compensation of cerebral circulation following occlusion of cranial (superior) vena cava. Fiziol. Zh. (Mosk.) 48, 684–691 (1962).

    Google Scholar 

  9. —, and L. G. Ormotsadze: Haemodynamic mechanisms underlying compensation of cerebral circulation following occlusion of cranial (superior) vena cava. Fed. Proc. 22, T 197–201 (1963).

    Google Scholar 

  10. —, and D. G. Baramidze: Functional peculiarities of the smaller arteries of the cerebral cortex (in Russian). Dokl. Acad. Nauk SSSR. 163, 529–532 (1965).

    Google Scholar 

  11. — and L. S. Nikolaishvili: Functional behaviour of pial and cortical arteries in conditions of increased metabolic demands of the cerebral cortex. Nature (Lond). 213, 506–507 (1967).

    Google Scholar 

  12. —, and M. G. Devdariani: Intrinsic mechanisms pertaining to the collateral circulation in the brain (in Russian with English summary). Path. Physiol. exp. Ther. (USSR) 8, No. 3, 20–24 (1964).

    Google Scholar 

  13. —, and L. S. Nikolaishvili: Investigation of physiological mechanisms correlating blood supply and functional state of the cerebral cortex (in Russian). Fiziol. Zh. (Mosk.) 52, 380–386 (1966).

    Google Scholar 

  14. —, and L. G. Ormotsadze: A haemodynamic regulating mechanism compensating for decreased blood supply to the cerebral cortex. Physiol. bohemoslov. 12, 100–105 (1963).

    Google Scholar 

  15. Owman, Ch., B. Falck, and G. I. Mchedlishvili: The adrenergic structures of pial arteries and their relations with the cerebral cortex (in Russian with English summary). Bull. biol. Med. exp. USSR. 50, No. 6, 98–101 (1965).

    Google Scholar 

  16. Penfield, W.: Intracerebral vascular nerves. Arch. Neurol. Psychiat. (Chic.) 27, 30–44 (1932).

    Google Scholar 

  17. Schneider, M.: Durchblutung und Sauerstoffversorgung des Gehirns, S. 25–48 Arbeitsgemeinschaft für Forschung des Landes Nordrhein- Westfalen. Köln u. Opladen: Westdeutscher Verlag 1966.

    Google Scholar 

  18. Sokoloff, L.: The action of drugs on the cerebral circulation. Pharmacol. Rev. 11, 1–85 (1959).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Physiologisches Institut der Georgischen Akademie der Wissenschaften, Tbilissi, UdSSR

    G. I. Mchedlishvili & L. S. Nikolaishvili

Authors
  1. G. I. Mchedlishvili
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. S. Nikolaishvili
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Erweiterte Form einer in Dokl. Akad. Nauk SSSR 156, 967 (1964) erschienenen Arbeit.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mchedlishvili, G.I., Nikolaishvili, L.S. Zum nervösen Mechanismus der funktionellen Dilatation der Piaarterien. Pflügers Archiv 296, 14–20 (1967). https://doi.org/10.1007/BF00363476

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00363476

Search

Navigation